Ermilova V D, Krylova M O
Arkh Patol. 1989;51(6):72-5.
Examination of two adenocystic carcinomas of the mammary gland has revealed main criteria for the morphological diagnosis of this malignant tumor. This is characterized by the presence of cribrose structures that are formed by multiple pseudocysts filled with amorphous substance. Clusters of small, monomorphic, cubic cells with round or oval nuclei form abundant islets at whose expense a characteristic sieveform pattern develops. The myoepithelial cells are frequently detected in the tumor. A favorable prognosis is seen in adenocystic carcinoma of the mammary gland. The two patients are alive having no signs of disease progression in their 9- and 51-month follow-up, respectively.
对两例乳腺腺囊癌的检查揭示了这种恶性肿瘤形态学诊断的主要标准。其特征是存在筛状结构,这些结构由多个充满无定形物质的假囊肿形成。小的、单形的、立方状细胞群,细胞核呈圆形或椭圆形,形成大量的细胞岛,在此基础上形成特征性的筛状模式。肿瘤中经常检测到肌上皮细胞。乳腺腺囊癌预后良好。两名患者均存活,在分别为期9个月和51个月的随访中均无疾病进展迹象。