Pigozzi María I
INBIOMED, Instituto de Investigaciones Biomédicas, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina.
Cytogenet Genome Res. 2016;150(2):128-138. doi: 10.1159/000453541. Epub 2016 Dec 29.
The cytological analysis of meiotic chromosomes is an exceptional tool to approach complex processes such as synapsis and recombination during the division. Chromosome studies of meiosis have been especially valuable in birds, where naturally occurring mutants or experimental knock-out animals are not available to fully investigate the basic mechanisms of major meiotic events. This review highlights the main contributions of synaptonemal complex and lampbrush chromosome research to the current knowledge of avian meiosis, with special emphasis on the organization of chromosomes during prophase I, the impact of chromosome rearrangements during meiosis, and distinctive features of the ZW pair.
减数分裂染色体的细胞学分析是研究诸如分裂过程中的联会和重组等复杂过程的一种特殊工具。减数分裂的染色体研究在鸟类中尤其有价值,因为在鸟类中无法获得自然发生的突变体或实验性基因敲除动物来全面研究主要减数分裂事件的基本机制。本综述重点介绍了联会复合体和灯刷染色体研究对当前鸟类减数分裂知识的主要贡献,特别强调了减数第一次分裂前期染色体的组织、减数分裂过程中染色体重排的影响以及ZW染色体对的独特特征。