Kaufman L M, Miller M T, Mafee M F
Department of Ophthalmology, University of Illinois, College of Medicine, Chicago 60612.
Arch Ophthalmol. 1989 Oct;107(10):1485-9. doi: 10.1001/archopht.1989.01070020559040.
Septo-optic dysplasia describes optic nerve hypoplasia in association with endocrine disturbances and/or midline brain malformations. Magnetic resonance imaging of the brain was used to study two patients with optic nerve hypoplasia, endocrine abnormalities, and normal midline brain anatomy on prior computed tomographic scan. The magnetic resonance imaging scans showed normal midline brain anatomy except for failure to visualize the pituitary stalk, a structure that magnetic resonance imaging has shown to be 100% sensitive in imaging in our normal controls. We propose that our two patients have endocrine abnormalities due to the discrete anomaly of pituitary stalk hypoplasia.
视隔发育不良是指视神经发育不全并伴有内分泌紊乱和/或中线脑畸形。脑部磁共振成像用于研究两名视神经发育不全、内分泌异常且先前计算机断层扫描显示中线脑解剖结构正常的患者。磁共振成像扫描显示中线脑解剖结构正常，但垂体柄未显影，而在我们的正常对照中，磁共振成像已显示垂体柄在成像中具有100%的敏感性。我们认为，我们的两名患者因垂体柄发育不全这一离散异常而出现内分泌异常。
