Bownik Adam, Stępniewska Zofia
Arh Hig Rada Toksikol. 2016 Dec 1;67(4):260-265. doi: 10.1515/aiht-2016-67-2837.
Ectoine is a compatible water molecule-binding solute (osmoprotectant) produced by several bacterial species in response to osmotic stress and unfavourable environmental conditions. This amino acid derivative can accumulate inside cells at high concentrations without interfering with natural processes and can protect the cell against radiation or osmotic stress. This brief review presents the current state of knowledge about the effects of ectoine on animals and focuses on its practical use for enzyme stabilisation, human skin protection, anti-inflammatory treatment, inhibitory effects in neurodegenerative diseases, and other therapeutic potential in human or veterinary medicine.
四氢嘧啶是几种细菌在应对渗透胁迫和不利环境条件时产生的一种相容性水分子结合溶质（渗透保护剂）。这种氨基酸衍生物可以在细胞内高浓度积累而不干扰自然过程，并且可以保护细胞免受辐射或渗透胁迫。这篇简短的综述介绍了关于四氢嘧啶对动物影响的当前知识状态，并重点关注其在酶稳定化、人类皮肤保护、抗炎治疗、神经退行性疾病抑制作用以及人类或兽医学中其他治疗潜力方面的实际应用。
