Camara-Lemarroy Carlos R, Ortiz-Zacarías Daniela, Peña-Avendaño Juan J, Estrada-Bellmann Ingrid, Villarreal-Velázquez Héctor J, Díaz-Torres Marco A
Servicio de Neurologia, Hospital Universitario "Dr. José E. González", Universidad Autonoma de Nuevo Leon, Mexico.
Servicio de Neurologia, Hospital Universitario "Dr. José E. González", Universidad Autonoma de Nuevo Leon, Mexico.
Epilepsy Behav. 2017 Jan;66:53-56. doi: 10.1016/j.yebeh.2016.10.021. Epub 2016 Dec 26.
People with epilepsy (PWE) are burdened by physical disability and side effects of antiepileptic drugs (AED) such as drowsiness and blurred vision. These factors place them at risk for reduced mobility and falls. The purpose of this study was to evaluate mobility and balance in PWE.
This was a cross-sectional study of PWE and age- and sex-matched controls. We evaluated mobility and balance using the Timed Up and Go Test (TUG) and the Tinetti Mobility Test (TMT). Self-reported confidence in balance was assessed using the Activities-Specific Balance Confidence Scale (ABC). Clinical and demographic characteristics and particularly epilepsy-related variables were recorded.
We included 33 PWE and 33 controls. PWE had a mean age of 36.7years, and 61% were male. They had a mean of 1.52 of seizures per month and used a mean of 1.6 anti-epileptic drugs (AEDs). PWE scored significantly worse in all measures (TUG, TMT, ABC) when compared with controls. PWE had poor performance in 60.6% of cases in the TUG and in 48.5% of cases in the TMT, compared to none in the control group. There was good correlation between the three instruments. TUG scores were correlated with epilepsy duration, but not age, seizure control or AED use. On multivariate logistic regression, poor performance TMT was significantly associated with poor confidence in balance, according to the ABC.
PWE have significant alterations in balance and mobility, independently of AED use or seizure control. These alterations are reflected in a poor self-reported confidence in carrying out daily activities.
癫痫患者（PWE）承受着身体残疾以及抗癫痫药物（AED）副作用的负担，如嗜睡和视力模糊。这些因素使他们面临活动能力下降和跌倒的风险。本研究的目的是评估癫痫患者的活动能力和平衡能力。
这是一项对癫痫患者以及年龄和性别匹配的对照组进行的横断面研究。我们使用定时起立行走测试（TUG）和Tinetti活动能力测试（TMT）评估活动能力和平衡能力。使用特定活动平衡信心量表（ABC）评估自我报告的平衡信心。记录临床和人口统计学特征，特别是与癫痫相关的变量。
我们纳入了33名癫痫患者和33名对照组。癫痫患者的平均年龄为36.7岁，61%为男性。他们每月平均发作1.52次，平均使用1.6种抗癫痫药物（AEDs）。与对照组相比，癫痫患者在所有测量指标（TUG、TMT、ABC）上的得分明显更差。在TUG测试中，60.6%的癫痫患者表现不佳，在TMT测试中，48.5%的癫痫患者表现不佳，而对照组无一例表现不佳。这三种测量工具之间存在良好的相关性。TUG得分与癫痫病程相关，但与年龄、癫痫控制或AED使用无关。在多因素逻辑回归分析中，根据ABC量表，TMT表现不佳与平衡信心差显著相关。
癫痫患者在平衡和活动能力方面有显著改变，与AED使用或癫痫控制无关。这些改变反映在自我报告的日常活动信心不足上。
