Condés-Lara M, León-Olea M, Sánchez-Alvarez M, Omaña-Zapata I
Bol Estud Med Biol. 1989 Jan-Jun;37(1-2):63-8.
We report the effects exerted by the cortex upon the intralaminar thalamic nucleic, as revealed by reversible blockade of the cortex with spreading depression in awake rats. Extracellular recordings of spontaneous activity were made simultaneously at thalamic and cortical sites. The effect of peripheral receptive field stimulation was to decrease activity of intralaminar thalamic cells. Cortical recordings revealed the cortical regions affected by spreading depression. Two type of cells were identified depending on the changes in their sensorial responses during the cortical spreading depression propagation. The first exhibited a tonic facilitating cortical control when the cortical spreading depression was located at A 8.0 to A 10.0. The second type exhibited a disappearance of the sensorial responses when cortical spreading depression was located at A 4.0 to A 8.0 and also displayed the tonic facilitating control. This indicates that two different identified cortical regions influenced the thalamic activity.
我们报告了在清醒大鼠中通过扩散性抑制对皮质进行可逆性阻断所揭示的皮质对丘脑板内核的作用。在丘脑和皮质部位同时进行细胞外自发活动记录。外周感受野刺激的作用是降低丘脑板内核细胞的活动。皮质记录显示了受扩散性抑制影响的皮质区域。根据皮质扩散性抑制传播过程中感觉反应的变化，鉴定出两种类型的细胞。第一种在皮质扩散性抑制位于A 8.0至A 10.0时表现出紧张性促进性皮质控制。第二种类型在皮质扩散性抑制位于A 4.0至A 8.0时感觉反应消失，并且也表现出紧张性促进性控制。这表明两个不同的已鉴定皮质区域影响了丘脑活动。
