Wong Phillip, Kashtwari Deeba, Nair Madhu K
Division of Oral and Maxillofacial Radiology, Oral and Maxillofacial Diagnostic Sciences/Radiology, Colleges of Dentistry/Medicine, University of Florida, Gainesville, FL, USA.
Imaging Sci Dent. 2016 Dec;46(4):273-278. doi: 10.5624/isd.2016.46.4.273. Epub 2016 Dec 20.
Plasma cell leukemia (PCL) is an aggressive form of multiple myeloma where there is hematogenous spread of abnormal plasma cells into the periphery. This is opposed to multiple myeloma, where the abnormal plasma cells stay in the bone marrow. PCL is more common in males than females, and is also more common in African-Americans than Caucasians. Signs and symptoms of PCL include, but are not limited to, renal insufficiency, hypercalcemia, anemia, lytic bone lesions, thrombocytopenia, hepatomegaly, and splenomegaly. Here, we discussed a case of a 71-year-old Caucasian female recently diagnosed with primary PCL with radiographic features of this disease throughout the body, with an emphasis on the maxillofacial skeleton and relevance from a dental standpoint.
浆细胞白血病（PCL）是多发性骨髓瘤的一种侵袭性形式，其特征为异常浆细胞经血行扩散至外周。这与多发性骨髓瘤不同，后者的异常浆细胞停留在骨髓中。PCL在男性中比女性更常见，在非裔美国人中比白种人更常见。PCL的体征和症状包括但不限于肾功能不全、高钙血症、贫血、溶骨性骨病变、血小板减少、肝肿大和脾肿大。在此，我们讨论了一例71岁白种女性近期诊断为原发性PCL的病例，该病例具有全身这种疾病的影像学特征，重点关注颌面部骨骼以及从牙科角度的相关性。
