SP Medical College, Bikaner, Rajasthan, India.
JLN Medical College, Ajmer, Ajmer, Rajasthan, India.
Mycopathologia. 2018 Aug;183(4):717-722. doi: 10.1007/s11046-016-0102-8. Epub 2016 Dec 29.
Mycotic keratitis, with its diverse clinical presentation and difficulties in treatment, makes it a challenging task for clinicians and an important object of study. The aim of present study was to determine the frequency of occurrence and epidemiological association with identification of fungal isolates from mycotic keratitis cases.
This was a prospective and observational study conducted in Mycology Laboratory, Department of Microbiology, S.P. Medical College, Bikaner, on corneal scrapings and swabs of a total of 480 patients attending the Ophthalmology OPD, P.B.M. Hospital, Bikaner, during July 2005 to June 2012.
Out of 480 suspected cases, 180 were found to be positive for fungus by smear/culture examination. Increased incidence was seen in the months of May to September with Aspergillus fumigatus being the most common isolate.
Mycotic keratitis, though an age-old disease, still presented with challenging aspects of diagnosis and treatment. The study showed fungal keratitis is prevalent in rural parts of north-west Rajasthan, mainly found in males (age group 21-40 years) with low socio-economic status (farm or factory workers). The most common cause of fungal keratitis was found to be species of Aspergillus.
真菌性角膜炎具有多样化的临床表现和治疗难度,这使得它成为临床医生的一项挑战,也是研究的重要对象。本研究的目的是确定从真菌性角膜炎病例中分离出的真菌的发生率和流行病学相关性。
这是一项在 2005 年 7 月至 2012 年 6 月期间,在比卡内尔的 P.B.M. 医院眼科门诊就诊的 480 名患者的角膜刮片和拭子中,于比卡内尔的微生物学系 SP 医学院真菌学实验室进行的前瞻性和观察性研究。
在 480 例疑似病例中,有 180 例通过涂片/培养检查发现呈阳性。5 月至 9 月的发病率增加,其中最常见的分离株是烟曲霉。
尽管真菌性角膜炎是一种古老的疾病,但它在诊断和治疗方面仍具有挑战性。该研究表明,在拉贾斯坦邦西北部的农村地区,真菌性角膜炎很普遍,主要发生在社会经济地位较低的男性(21-40 岁)中,他们主要是农民或工厂工人。真菌性角膜炎的最常见病因是曲霉菌属的菌种。