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光学相干断层扫描:一种用于测量神经退行性变并促进多发性硬化症组织保护新疗法测试的定量工具。

Optical coherence tomography: A quantitative tool to measure neurodegeneration and facilitate testing of novel treatments for tissue protection in multiple sclerosis.

作者信息

Gordon-Lipkin Eliza, Calabresi Peter A

机构信息

Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

出版信息

J Neuroimmunol. 2017 Mar 15;304:93-96. doi: 10.1016/j.jneuroim.2016.12.003. Epub 2016 Dec 14.

Abstract

Optical coherence tomography (OCT) is a relatively new imaging technology that has been introduced as a powerful biomarker in neurological disease, including multiple sclerosis. In this review, OCT as an imaging technique, its reproducibility and validation in multiple sclerosis, application to other neurodegenerative diseases and future technological directions are discussed.

摘要

光学相干断层扫描(OCT)是一种相对较新的成像技术,已被引入作为包括多发性硬化症在内的神经疾病的一种强大生物标志物。在本综述中,将讨论OCT作为一种成像技术、其在多发性硬化症中的可重复性和验证、在其他神经退行性疾病中的应用以及未来的技术发展方向。

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