Section for Translational Psychobiology in Child and Adolescent Psychiatry, Department of Child and Adolescent Psychiatry, Centre for Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany.
Department of Child and Adolescent Psychiatry, Centre for Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany.
Psychiatry Res. 2017 Feb;248:117-120. doi: 10.1016/j.psychres.2016.12.024. Epub 2016 Dec 21.
Vagally mediated heart rate variability (vmHRV) is reduced in borderline personality disorder (BPD). Non-suicidal self-injury (NSSI) is associated with comorbid psychopathology, in particular BPD. We aimed to examine differences in cardiac function (vmHRV and heart rate [HR]) comparing adolescents (12-17 years) engaging in NSSI (n=30) and healthy controls (n=30). Further, we aimed to determine clinical concomitants of cardiac function in patients with NSSI. Analyses showed no significant group differences on cardiac function. Controlling for a host of confounding variables resting state HR and vmHRV in adolescents with NSSI were significantly correlated with BPD symptoms and the current level of functioning.
边缘型人格障碍（BPD）患者的迷走神经介导的心率变异性（vmHRV）降低。非自杀性自伤（NSSI）与合并的精神病理学有关，特别是 BPD。我们旨在通过比较患有 NSSI 的青少年（12-17 岁，n=30）和健康对照组（n=30），来探讨心脏功能（vmHRV 和心率[HR]）的差异。此外，我们旨在确定患有 NSSI 的患者心脏功能的临床伴随物。分析显示，心脏功能方面两组之间无显著差异。控制了大量混杂变量后，NSSI 青少年的静息状态 HR 和 vmHRV 与 BPD 症状和当前功能水平显著相关。
