Kuok Chi-Hang, Huang Chung-Hsin, Tsai Pei-Shan, Ko Yuan-Pi, Lee Wei-Shih, Hsu Yung-Wei, Hung Fang-Yu
Department of Anesthesiology, Hsinchu Mackay Memorial Hospital, Hsinchu City, Taiwan.
Department of Anesthesiology, Hsinchu Mackay Memorial Hospital, Hsinchu City, Taiwan.
Taiwan J Obstet Gynecol. 2016 Dec;55(6):810-814. doi: 10.1016/j.tjog.2015.04.009.
Lumbosacral cerebrospinal fluid volume is decreased as the enlarging uterus compresses the inferior vena cava during pregnancy. A subsequent greater cephalad spread of sensory blockade is observed. Gravid uterus plays a crucial role in affecting the spinal anesthesia level. We hypothesized that maternal abdominal circumference can reflect compressive effect of the uterus and investigated the relationship between abdominal circumference and the level of sensory blockade, and incidence of hypotension following spinal anesthesia with hyperbaric bupivacaine in term parturients.
Forty-two term parturients scheduled for elective cesarean section were studied. Abdominal circumference was measured before spinal anesthesia; 0.5% hyperbaric bupivacaine (2 mL, 2.2 mL, or 2.4 mL) was injected in to the subarachnoid space at the L3-L4 intervertebral level according to the parturient's height. The level of sensory blockade was assessed using an ice cube 1 minute, 5 minutes, 10 minutes, and 15 minutes after the spinal injection. The level of sensory blockade at the 15 minute was defined as the level of maximum sensory blockade. Statistical correlation coefficients were evaluated with Spearman's rank correlation.
The correlation coefficient between the abdominal circumference and spinal level measured by cold sensation loss at 5 minutes after spinal anesthesia was significantly positive (right side ρ=0.43, p=0.005; left side ρ=0.46, p=0.003). No significant correlation was found between abdominal circumference and the level of maximum sensory blockade, the incidence of hypotension, ephedrine dosage, nausea, and vomiting after spinal anesthesia.
Parturients with greater abdominal circumference value have a higher level of sensory blockade at 5 minutes after spinal anesthesia. Abdominal circumference cannot predict the maximum sensory blockade level and the incidence of hypotension.
孕期子宫增大压迫下腔静脉,导致腰骶部脑脊液容量减少。随后观察到感觉阻滞向头端的扩散范围更大。妊娠子宫在影响脊麻平面方面起关键作用。我们推测孕妇腹围可反映子宫的压迫作用,并研究了腹围与感觉阻滞平面以及足月产妇腰麻后低血压发生率之间的关系。
研究对象为42例计划行择期剖宫产的足月产妇。在腰麻前测量腹围;根据产妇身高,于L3-L4椎间隙向蛛网膜下腔注入0.5%的重比重布比卡因(2 mL、2.2 mL或2.4 mL)。在腰麻注射后1分钟、5分钟、10分钟和15分钟,用冰块评估感觉阻滞平面。将15分钟时的感觉阻滞平面定义为最大感觉阻滞平面。采用Spearman等级相关评估统计相关系数。
腰麻后5分钟通过冷觉丧失测量的腹围与脊髓平面之间的相关系数呈显著正相关(右侧ρ=0.43,p=0.005;左侧ρ=0.46,p=0.003)。腹围与最大感觉阻滞平面、低血压发生率、麻黄碱用量、腰麻后恶心和呕吐之间未发现显著相关性。
腹围值较大的产妇在腰麻后5分钟时感觉阻滞平面较高。腹围不能预测最大感觉阻滞平面和低血压发生率。