• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

TERT Promoter Mutations Occur Frequently in Urothelial Papilloma and Papillary Urothelial Neoplasm of Low Malignant Potential.

作者信息

Cheng Liang, Montironi Rodolfo, Lopez-Beltran Antonio

机构信息

Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Urology, Indiana University School of Medicine, Indianapolis, IN, USA.

Institute of Pathological Anatomy and Histopathology, School of Medicine, Polytechnic University of the Marche Region (Ancona), United Hospitals, Ancona, Italy.

出版信息

Eur Urol. 2017 Mar;71(3):497-498. doi: 10.1016/j.eururo.2016.12.008. Epub 2016 Dec 28.

DOI:10.1016/j.eururo.2016.12.008
PMID:28040359
Abstract
摘要

相似文献

1
TERT Promoter Mutations Occur Frequently in Urothelial Papilloma and Papillary Urothelial Neoplasm of Low Malignant Potential.端粒酶逆转录酶（TERT）启动子突变在尿路上皮乳头状瘤和低恶性潜能乳头状尿路上皮肿瘤中频繁发生。
Eur Urol. 2017 Mar;71(3):497-498. doi: 10.1016/j.eururo.2016.12.008. Epub 2016 Dec 28.
2
Implications of TERT promoter mutations and telomerase activity in urothelial carcinogenesis.TERT 启动子突变与端粒酶活性在尿路上皮肿瘤发生中的意义。
Nat Rev Urol. 2018 Jun;15(6):386-393. doi: 10.1038/s41585-018-0001-5.
3
Telomerase reverse transcriptase (TERT) promoter mutation analysis of benign, malignant and reactive urothelial lesions reveals a subpopulation of inverted papilloma with immortalizing genetic change.良性、恶性和反应性尿路上皮病变的端粒酶逆转录酶（TERT）启动子突变分析揭示了具有永生化基因改变的内翻性乳头状瘤亚群。
Histopathology. 2016 Jul;69(1):107-13. doi: 10.1111/his.12920. Epub 2016 Feb 11.
4
Biological significance of TERT promoter mutation in papillary urothelial neoplasm of low malignant potential.TERT 启动子突变在低级别尿路上皮乳头状肿瘤中的生物学意义。
Histopathology. 2018 Apr;72(5):795-803. doi: 10.1111/his.13441. Epub 2018 Jan 4.
5
Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer.癌症。膀胱癌中 TERT 启动子突变与端粒酶激活。
Science. 2015 Feb 27;347(6225):1006-10. doi: 10.1126/science.1260200. Epub 2015 Feb 5.
6
TERT C228T mutation in non-malignant bladder urothelium is associated with intravesical recurrence for patients with non-muscle invasive bladder cancer.TERT C228T 突变与非肌层浸润性膀胱癌患者的膀胱内复发相关。
Mol Oncol. 2020 Oct;14(10):2375-2383. doi: 10.1002/1878-0261.12746. Epub 2020 Jun 27.
7
Promoter Mutation Analysis of Whole-Organ Mapping Bladder Cancers.全器官图谱膀胱癌的启动子突变分析。
Genes (Basel). 2021 Feb 5;12(2):230. doi: 10.3390/genes12020230.
8
Recurrent TERT promoter mutations in urothelial carcinoma and potential clinical applications.复发性 TERT 启动子突变在尿路上皮癌中的作用及其潜在的临床应用。
Ann Diagn Pathol. 2016 Apr;21:7-11. doi: 10.1016/j.anndiagpath.2015.12.002. Epub 2015 Dec 17.
9
Telomerase reverse transcriptase promoter mutations in bladder cancer: high frequency across stages, detection in urine, and lack of association with outcome.膀胱癌中端粒酶逆转录酶启动子突变：跨越多个阶段的高频率、尿液中的检测以及与结局无关。
Eur Urol. 2014 Feb;65(2):360-6. doi: 10.1016/j.eururo.2013.08.052. Epub 2013 Sep 7.
10
TERT promoter mutations occur early in urothelial neoplasia and are biomarkers of early disease and disease recurrence in urine.TERT 启动子突变发生于尿路上皮肿瘤早期，是尿液中早期疾病和疾病复发的生物标志物。
Cancer Res. 2013 Dec 15;73(24):7162-7. doi: 10.1158/0008-5472.CAN-13-2498. Epub 2013 Oct 11.

引用本文的文献

1
An overview of the role of telomeres and telomerase in pre‑neoplastic lesions (Review).端粒和端粒酶在肿瘤前病变中的作用概述（综述）
Mol Clin Oncol. 2023 Jun 22;19(2):61. doi: 10.3892/mco.2023.2657. eCollection 2023 Aug.
2
Role of telomere length in human carcinogenesis (Review).端粒长度在人类肿瘤发生中的作用（综述）。
Int J Oncol. 2023 Jul;63(1). doi: 10.3892/ijo.2023.5526. Epub 2023 May 26.
3
promoter mutations and methylation for telomerase activation in urothelial carcinomas: New mechanistic insights and clinical significance.
膀胱癌中端粒酶激活的启动子突变和甲基化：新的机制见解和临床意义。
Front Immunol. 2023 Jan 12;13:1071390. doi: 10.3389/fimmu.2022.1071390. eCollection 2022.
4
Detection of Promoter Mutations as a Prognostic Biomarker in Gliomas: Methodology, Prospects, and Advances.检测启动子突变作为胶质瘤的预后生物标志物：方法、前景与进展
Biomedicines. 2022 Mar 21;10(3):728. doi: 10.3390/biomedicines10030728.
5
Promoter Mutations in Keratinizing and Nonkeratinizing Squamous Metaplasia of the Urinary Tract.泌尿道角化和非角化鳞状化生中的启动子突变
Eur Urol Open Sci. 2022 Jan 3;35:74-78. doi: 10.1016/j.euros.2021.11.007. eCollection 2022 Jan.
6
Distinctive morphological and molecular features of urothelial carcinoma with an inverted growth pattern.具有内翻生长模式的尿路上皮癌的独特形态学和分子特征。
J Pathol Transl Med. 2021 Jul;55(4):239-246. doi: 10.4132/jptm.2021.04.20. Epub 2021 Jun 14.
7
Genomic landscape of inverted urothelial papilloma and urothelial papilloma of the bladder.膀胱内翻性尿路上皮乳头瘤和尿路上皮乳头瘤的基因组景观。
J Pathol. 2019 Jul;248(3):260-265. doi: 10.1002/path.5261. Epub 2019 Apr 22.
8
Preoperative serum apolipoprotein A-I levels predict long-term survival in non-muscle-invasive bladder cancer patients.术前血清载脂蛋白A-I水平可预测非肌层浸润性膀胱癌患者的长期生存情况。
Cancer Manag Res. 2018 May 14;10:1177-1190. doi: 10.2147/CMAR.S165213. eCollection 2018.
9
Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy.通过分析驱动基因突变和非整倍体进行尿路上皮癌的无创检测。
Elife. 2018 Mar 20;7:e32143. doi: 10.7554/eLife.32143.
10
Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer.人类端粒酶逆转录酶 (hTERT) 调控机制：癌症中的临床影响。
J Biomed Sci. 2018 Mar 12;25(1):22. doi: 10.1186/s12929-018-0422-8.