磁共振成像引导下的前列腺近距离放射治疗功能解剖学方法。
Magnetic resonance imaging-guided functional anatomy approach to prostate brachytherapy.
作者信息
Soni Payal D, Berlin Alejandro, Venkatesan Aradhana M, McLaughlin Patrick W
机构信息
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI.
Department of Radiation Oncology, Princess Margaret Cancer Centre, Toronto, ON, Canada.
出版信息
Brachytherapy. 2017 Jul-Aug;16(4):698-714. doi: 10.1016/j.brachy.2016.11.009. Epub 2016 Dec 29.
PURPOSE
To provide an MRI based functional anatomy guide to prostate brachytherapy.
METHODS AND MATERIALS
We performed a narrative review of periprostatic functional anatomy and the significance of this anatomy in prostate brachytherapy treatment planning.
RESULTS
MRI has improved delineation of gross tumor and critical periprostatic structures that have been implicated in toxicity. Furthermore, MRI has revealed the significant anatomic variants and the dynamic nature of these structures that can have significant implications for treatment planning and dosimetry.
CONCLUSIONS
The MRI-based functional anatomy approach to prostate brachytherapy takes into account extent of disease, its relation to the patient's individual anatomy, and functional baseline to optimize the therapeutic ratio of prostate cancer treatment.
目的
提供基于MRI的前列腺近距离放射治疗功能解剖学指南。
方法与材料
我们对前列腺周围功能解剖学及其在前列腺近距离放射治疗计划中的意义进行了叙述性综述。
结果
MRI改善了对大体肿瘤和与毒性相关的关键前列腺周围结构的勾画。此外，MRI还揭示了这些结构的显著解剖变异及其动态特性，这对治疗计划和剂量测定可能具有重要意义。
结论
基于MRI的前列腺近距离放射治疗功能解剖学方法考虑了疾病范围、其与患者个体解剖结构的关系以及功能基线，以优化前列腺癌治疗的治疗比。
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