Safran D, Pelouze G, Roujas F
Ann Anesthesiol Fr. 1978;19(3):214-8.
A study of the haemodynamic effects of an injection of 0.3 mg/kg of Etomidate was carried out in 11 multiple trauma patients under constant controlled ventilation. At the 3 rd minute after injection there was a slight, but significant, increase in cardiac output and in the systolic index of the left ventricle, persisting at the 20th minute. It may be concluded that the injection of a dose of 0.3 mg/kg has no harmful haemodynamic effects in this type of patient.
对11名在持续控制通气下的多发伤患者注射0.3mg/kg依托咪酯后的血流动力学效应进行了研究。注射后第3分钟,心输出量和左心室收缩指数略有但显著增加,并持续至第20分钟。可以得出结论,注射0.3mg/kg的剂量对这类患者没有有害的血流动力学影响。