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[阿片类药物自杀未遂后迟发性缺氧后白质脑病]

[Delayed posthypoxic leucoencephalopathy after suicide attempt with opioids].

作者信息

Amiri Moshgan, Larsen Line Sofie Lunde

出版信息

Ugeskr Laeger. 2016 Dec 19;178(51).

PMID:28041543
Abstract

Delayed posthypoxic leucoencephalopathy (DPHL) is a rare condition with manifestation of neurological and neuropsychological symptoms, following an acute hypoxic condition with an intermittent recovery period of four weeks. MRI findings show symmetric subcortical white matter lesions. We present a patient admitted with symptoms and brain MRI-scan consistent with DPHL. Four weeks prior the patient had tried to commit suicide with opioids. DPHL should be considered in patients with subacute onset of neurological and neuropsychological symptoms after an acute hypoxic condition of the brain.

摘要

迟发性缺氧后白质脑病(DPHL)是一种罕见疾病,在急性缺氧状况后伴有四周间歇性恢复期,表现为神经和神经心理症状。MRI检查结果显示对称的皮质下白质病变。我们报告了一名因症状及脑部MRI扫描结果符合DPHL而入院的患者。该患者四周前曾试图服用阿片类药物自杀。对于脑部急性缺氧状况后出现亚急性神经和神经心理症状的患者,应考虑迟发性缺氧后白质脑病。

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