Denstedt Ellen B
Ontario Veterinary College, University of Guelph, 50 Stone Road East Guelph, Ontario N1G 2W1.
Can Vet J. 2017 Jan;58(1):83-86.
An 8-year-old spayed Portuguese water dog was presented with dysuria, lethargy, and anorexia. A profound neutropenia and pancytopenia were identified. Bone marrow aspirates revealed neutrophilic hyperplasia, a significant left shift, and toxic changes, suggesting immune-mediated destruction as a likely underlying mechanism. Immunosuppressive therapy was instituted and clinical signs improved.
一只8岁已绝育的葡萄牙水犬出现排尿困难、嗜睡和厌食症状。检查发现严重的中性粒细胞减少和全血细胞减少。骨髓穿刺显示中性粒细胞增生、明显的核左移和中毒性改变，提示免疫介导的破坏可能是潜在机制。遂开始进行免疫抑制治疗，临床症状有所改善。
