Aguilera-Castro Lara, Ferre-Aracil Carlos, Garcia-Garcia-de-Paredes Ana, Rodriguez-de-Santiago Enrique, Lopez-Sanroman Antonio
Gastroenterology and Hepatology Department, University Hospital Ramón y Cajal (affiliated with Universidad de Alcalá), Madrid, Spain.
Ann Gastroenterol. 2017;30(1):33-44. doi: 10.20524/aog.2016.0099. Epub 2016 Oct 27.
Patients with Crohn's disease often develop perianal disease, successfully managed in most cases. However, its most aggressive form, complex perianal disease, is associated with high morbidity and a significant impairment in patients' quality of life. The aim of this review is to provide an updated approach to this condition, reviewing aspects of its epidemiology, diagnosis and therapeutic alternatives. Emerging treatment options are also discussed. A multidisciplinary assessment of these patients with a coordinated medical and surgical approach is crucial.
克罗恩病患者常出现肛周疾病,多数情况下能得到成功治疗。然而,其最严重的形式,即复杂性肛周疾病,与高发病率及患者生活质量的显著受损相关。本综述的目的是提供针对这种情况的最新方法,回顾其流行病学、诊断及治疗选择等方面。还将讨论新兴的治疗方案。对这些患者采用多学科评估并结合协调的内科和外科治疗方法至关重要。