Beckmann Nicholas M
Department of Diagnostic and Interventional Imaging, UT Health, Houston, TX, USA.
Radiol Res Pract. 2016;2016:4801474. doi: 10.1155/2016/4801474. Epub 2016 Nov 30.
Calcium apatite deposition disease (CADD) is a common entity characterized by deposition of calcium apatite crystals within and around connective tissues, usually in a periarticular location. CADD most frequently involves the rotator cuff. However, it can theoretically occur in almost any location in the musculoskeletal system, and many different locations of CADD have been described. When CADD presents in an unexpected location it can pose a diagnostic challenge, particularly when associated with pain or swelling, and can be confused with other pathologic processes, such as infection or malignancy. However, CADD has typical imaging characteristics that usually allows for a correct diagnosis to be made without additional imaging or laboratory workup, even when presenting in unusual locations. This is a review of the common and uncommon presentations of CADD in the appendicular and axial skeleton as well as an updated review of pathophysiology of CADD and current treatments.
钙磷灰石沉积病（CADD）是一种常见病症，其特征为钙磷灰石晶体在结缔组织内及周围沉积，通常位于关节周围。CADD最常累及肩袖。然而，理论上它几乎可发生于肌肉骨骼系统的任何部位，且已有许多不同部位CADD的报道。当CADD出现在意想不到的部位时，可能会带来诊断挑战，尤其是伴有疼痛或肿胀时，可能会与其他病理过程（如感染或恶性肿瘤）相混淆。然而，CADD具有典型的影像学特征，即使出现在不寻常部位，通常也无需额外的影像学检查或实验室检查就能做出正确诊断。本文综述了CADD在四肢骨骼和中轴骨骼的常见及罕见表现，以及CADD病理生理学和当前治疗方法的最新综述。
