[促细胞生长素对实验性肝损伤的血管保护作用]
[Angio-protective effect of catergen in experimental liver injury].
作者信息
Gaskina T K, Gorchakov V N, Kurilovich S A
出版信息
Biull Eksp Biol Med. 1989 Jul;108(7):28-30.
PMID:2804291
Abstract
The 120 male rats were exposed to CCl4(1 mg/kg) or ethanol (6 g/kg) to produce acute liver injury. Previous injection of cathergen (+)-cyanidonol-3) decreased the region of hepatocytes necrosis, stabilized microvessels diameter and increased muss cells degranulation. These results indicate hepatoprotective and angioprotective effect of cathergen, more expressed in exposure CCl4.
摘要
将120只雄性大鼠暴露于四氯化碳（1毫克/千克）或乙醇（6克/千克）中以产生急性肝损伤。预先注射卡托根（（+）-氰基多醇-3）可减少肝细胞坏死区域，稳定微血管直径并增加肌肉细胞脱颗粒。这些结果表明卡托根具有肝保护和血管保护作用，在四氯化碳暴露中表现更为明显。
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