Kravtsov G M, Dulin N O, Postnov Iu V
Biull Eksp Biol Med. 1989 Jul;108(7):42-4.
Protein kinase C activities in the brain tissue of spontaneously hypertensive rats (SHR) and normotensive control rats (WKY) were studied. Protein kinase C activity in SHR was found to be 35% higher than that in normotensive control rats. It is suggested that the increase in protein kinase C activity is involved in the mechanism of membrane alterations in primary hypertension.
研究了自发性高血压大鼠(SHR)和正常血压对照大鼠(WKY)脑组织中的蛋白激酶C活性。发现SHR中的蛋白激酶C活性比正常血压对照大鼠高35%。提示蛋白激酶C活性增加参与了原发性高血压中膜改变的机制。