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[自发性高血压大鼠脑组织中的蛋白激酶C活性]

[Protein kinase C activity in the brain tissue of spontaneously hypertensive rats].

作者信息

Kravtsov G M, Dulin N O, Postnov Iu V

出版信息

Biull Eksp Biol Med. 1989 Jul;108(7):42-4.

PMID:2804296
Abstract

Protein kinase C activities in the brain tissue of spontaneously hypertensive rats (SHR) and normotensive control rats (WKY) were studied. Protein kinase C activity in SHR was found to be 35% higher than that in normotensive control rats. It is suggested that the increase in protein kinase C activity is involved in the mechanism of membrane alterations in primary hypertension.

摘要

研究了自发性高血压大鼠（SHR）和正常血压对照大鼠（WKY）脑组织中的蛋白激酶C活性。发现SHR中的蛋白激酶C活性比正常血压对照大鼠高35%。提示蛋白激酶C活性增加参与了原发性高血压中膜改变的机制。

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