Dobrynin V P, Sovetov A N, Pogozheva E N, Lutsenko V K, Ter-Minasian M K
Biull Eksp Biol Med. 1989 Jul;108(7):5-7.
Peptide extracts of the right and left hemispheres were applied to the projective (somatosensory and visual) and temporal associative regions of the left brain hemisphere in cats. In the zones of peptide application, evoked potentials (EP) in response to singular and coupled somatic, visual and transcallosal stimuli were registered. The data obtained showed that right and left peptide extracts had different effects on evoked potentials of the left hemisphere. Thus ipsilateral extract increased the amplitude of projective EP, decreased duration of their cycles and amplitude of transcallosal responses. Contralateral extract, on the contrary, activated interhemispheric inputs to brain cortex, suppressed thalamic inputs and increased multimodal properties of neurons. A differential approach to the problem of specific correction of pathological states of the right and left brain hemispheres is required. Right and left peptide extracts may be used in normalization of interhemispheric activity balance in compensatory-recovering processes.
将猫左右脑半球的肽提取物应用于左脑半球的投射性（躯体感觉和视觉）及颞叶联合区域。在肽应用区域，记录了对单个及耦合的躯体、视觉和胼胝体间刺激的诱发电位（EP）。所获数据表明，左右肽提取物对左半球的诱发电位有不同影响。因此，同侧提取物增加了投射性EP的幅度，缩短了其周期时长并降低了胼胝体间反应的幅度。相反，对侧提取物激活了大脑皮层的半球间输入，抑制了丘脑输入并增强了神经元的多模态特性。需要采用不同方法来解决左右脑半球病理状态的特异性纠正问题。左右肽提取物可用于在代偿恢复过程中使半球间活动平衡正常化。
