Molodsova G F, Il'iuchenok R Iu
Biull Eksp Biol Med. 1989 Jul;108(7):51-2.
5-HT1 receptors of the amygdala, midbrain's central gray substance, hippocampus and frontal cortex of the rats were investigated during the memory trace retrieval, using the model of "psychogenic" amnesia. It was found that specific binding of 3H 5-HT in amygdala and central gray substance was decreased in the rats with passive avoidance retention. 3H 5-HT binding in the amnesic rats didn't differ from the control animals. Absence of decrease of 5-HT1 receptors number could be considered as one of the possible mechanisms of the memory trace non-retrieval due to amnesia or its consequence.
利用“心因性”失忆模型，在记忆痕迹检索期间对大鼠杏仁核、中脑中央灰质、海马体和额叶皮质的5-羟色胺1（5-HT1）受体进行了研究。结果发现，被动回避记忆保留的大鼠杏仁核和中央灰质中3H 5-HT的特异性结合减少。失忆大鼠中3H 5-HT的结合与对照动物无差异。5-HT1受体数量未减少可被视为失忆导致记忆痕迹无法检索或其后果的可能机制之一。
