Chugh Shikha, Garg Vijay Kumar, Sarkar Rashmi, Sardana Kabir
1 Department of Dermatology, Lok Nayak Hospital, Maulana Azad Medical College, New Delhi, India.
2 Department of Dermatology, Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, New Delhi, India.
J Int Assoc Provid AIDS Care. 2017 Jul/Aug;16(4):331-337. doi: 10.1177/2325957416686196. Epub 2017 Jan 3.
Sexually transmitted diseases are a major public health problem both in developing and in developed countries, and especially with the co-synergy with HIV infection, there is an increasing need to have a proper understanding of the clinicodemographic patterns of sexually transmitted infections (STIs) for planning and implementing control strategies. Worldwide, there is an increased preponderance of viral STIs. Increasing incidence and altered clinical presentation of viral STIs in patients with HIV pose a diagnostic challenge; thereby, we studied the demographic profile of HIV-seropositive patients and compared clinical manifestations of viral STIs in HIV-seropositive patients to those in seronegative individuals. Twenty-seven HIV-seropositive patients with viral STI (herpes/molluscum/warts) and same number of age-, sex-, and STI-matched seronegative patients were studied for variability in clinical profile. There were significant differences in the demographic factors (education, income, and migration) and sexual practices (number of contacts and source of infection) in the 2 groups. Lesional symptoms, increased extent of lesions, and resistance to treatment were significantly more common in HIV-seropositive patients.
性传播疾病在发展中国家和发达国家都是一个主要的公共卫生问题，尤其是与艾滋病毒感染协同作用时，为了规划和实施控制策略，越来越需要正确了解性传播感染（STIs）的临床人口统计学模式。在全球范围内，病毒性性传播感染的比例在增加。艾滋病毒患者中病毒性性传播感染发病率的上升和临床表现的改变带来了诊断挑战；因此，我们研究了艾滋病毒血清阳性患者的人口统计学特征，并将艾滋病毒血清阳性患者中病毒性性传播感染的临床表现与血清阴性个体进行了比较。对27例患有病毒性性传播感染（疱疹/传染性软疣/疣）的艾滋病毒血清阳性患者以及相同数量的年龄、性别和性传播感染相匹配的血清阴性患者的临床特征变异性进行了研究。两组在人口统计学因素（教育程度、收入和移民情况）和性行为（性接触次数和感染源）方面存在显著差异。病变症状、病变范围扩大和治疗抵抗在艾滋病毒血清阳性患者中明显更为常见。
