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冷冻消融治疗与电视辅助微创二尖瓣手术同时发生的心房颤动的结果

Results of Cryoablation for Atrial Fibrillation Concomitant With Video-Assisted Minimally Invasive Mitral Valve Surgery.

作者信息

Marchetto Giovanni, Anselmino Matteo, Rovera Chiara, Mancuso Samuel, Ricci Davide, Antolini Marina, Morello Mara, Gaita Fiorenzo, Rinaldi Mauro

机构信息

Department of Surgical Sciences, Città della Salute e della Scienza di Torino Hospital, University of Turin, Turin, Italy; Department of Medical Sciences, Città della Salute e della Scienza di Torino Hospital, University of Turin, Turin, Italy.

Department of Medical Sciences, Città della Salute e della Scienza di Torino Hospital, University of Turin, Turin, Italy.

出版信息

Semin Thorac Cardiovasc Surg. 2016;28(2):271-280. doi: 10.1053/j.semtcvs.2016.04.006. Epub 2016 Apr 21.

Abstract

Interest in minimally invasive video-assisted mitral valve surgery (MIMVS) is rapidly growing. Data on concomitant atrial fibrillation (AF) ablation to MIMVS are still lacking. The present study investigates the long-term results of AF cryoablation concomitant to MIMVS. From October 2006-September 2014, 68 patients with mitral valve disease (age 65.9 ± 11.1 years, 34 men out of 68 patients, Euroscore log 5.4 ± 4.5) and drug-resistant AF underwent MIMVS via right minithoracotomy and concomitant left-sided AF endocardial cryoablation (Cryoflex Medtronic, Minneapolis, MN). Patients were independently followed up by cardiological outpatient visits and underwent electrophysiological study when indicated. In total, 44 out of 68 patients (64.7%) underwent mitral valve repair and 8 patients (11.8%) also received concomitant tricuspid valve surgery. One procedure was electively converted to full sternotomy (1.5%). Total clamp time was 97.6 ± 22.8 minutes. In March 2015, 60 patients were alive and completed the follow-up after a mean of 3.4 ± 2.0 years following the procedure. In all, 48 patients (80%) presented sinus rhythm throughout the whole follow-up. Freedom from AF was respectively 95%, 87%, and 72% at 1, 3, and 5 years, respectively. We recorded 2 pacemaker implants (3.3%). A total of 3 patients suffered symptomatic recurrences (2 atypical atrial flutter and 1 atrial fibrillation) and underwent transcatheter ablation-all the 3 patients remained in stable sinus rhythm for the remaining follow-up. In conclusions, given the favorable long-term sinus rhythm maintenance rates of concomitant cryoablation, MIMVS can also be offered to patients with symptomatic AF. AF transcatheter ablation may easily avoid further symptomatic recurrences.

摘要

对微创视频辅助二尖瓣手术(MIMVS)的兴趣正在迅速增长。关于MIMVS联合心房颤动(AF)消融的数据仍然缺乏。本研究调查了MIMVS联合AF冷冻消融的长期结果。从2006年10月至2014年9月,68例二尖瓣疾病患者(年龄65.9±11.1岁,68例患者中有34例男性,欧洲心脏手术风险评估系统(Euroscore)评分为5.4±4.5)和药物难治性AF通过右胸小切口接受MIMVS并同时进行左侧AF心内膜冷冻消融(美敦力公司的Cryoflex,明尼阿波利斯,明尼苏达州)。患者由心脏病门诊独立随访,并在有指征时接受电生理研究。68例患者中,共有44例(64.7%)接受了二尖瓣修复,8例(11.8%)还接受了同期三尖瓣手术。1例手术选择性转为全胸骨切开术(1.5%)。总夹闭时间为97.6±22.8分钟。2015年3月,60例患者存活并在手术后平均3.4±2.0年完成随访。总体而言,48例患者(80%)在整个随访期间呈现窦性心律。1年、3年和5年时无AF的发生率分别为95%、87%和72%。我们记录了2例起搏器植入(3.3%)。共有3例患者出现症状复发(2例非典型心房扑动和1例心房颤动)并接受了经导管消融——所有3例患者在剩余随访期间均维持稳定的窦性心律。总之,鉴于联合冷冻消融具有良好的长期窦性心律维持率,MIMVS也可用于有症状AF的患者。AF经导管消融可轻松避免进一步的症状复发。

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