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机器人辅助与传统微创二尖瓣修复术同期行冷冻消融术的倾向匹配比较。

A propensity matched comparison of robotic traditional minimal access approach for mitral valve repair with concomitant cryoablation.

作者信息

Rufa Magdalena, Nagib Ragi, Aktuerk Dincer, Ahad Samir, Ghinescu Mihnea, Franke Ulrich

机构信息

Department of Cardiovascular Surgery, Robert Bosch Hospital, Stuttgart, Germany.

Barts Heart Centre, Barts Health NHS, London, UK.

出版信息

J Thorac Dis. 2023 Dec 30;15(12):6459-6474. doi: 10.21037/jtd-23-1306. Epub 2023 Dec 5.

Abstract

BACKGROUND

Atrial fibrillation (AF) occurs frequently in patients with mitral valve disease. Results of cryoablation concomitant with either minimally invasive video-assisted [minimally invasive mitral valve surgery (MIMVS)] or with robotic-assisted (RMV) mitral valve surgery have previously been separately reported. However, there are up-to-date no studies comparing the two procedures in terms of safety, efficacy, and mid-term follow-up.

METHODS

Between January 2017 and March 2022, 294 patients underwent MIMVS, and 187 patients underwent RMV at our institution. After 1:1 propensity score matching using 22 preoperative variables, the study included 104 patients. Group 1 (MIMVS) included 52 patients operated on between 2017-2022 using a minimally invasive video-assisted right-sided mini-thoracotomy. Group 2 (RMV) included 52 patients operated on between 2019-2021 using a robotic-assisted approach. Early and mid-term outcomes were assessed, including maintenance of sinus rhythm. Follow-up was 100% complete at a median follow-up of 2 years.

RESULTS

For the entire propensity matched cohort, the median EuroSCORE II was 3.14 [interquartile range (IQR), 1.93-4.99], the median age was 68 (IQR, 61-74) years, and two thirds of the patients were male. Most (72.1%) underwent mitral valve surgery, and 26.9% had an additional tricuspid procedure. Only four patients underwent mitral valve replacement (3.8%). The majority (87.5%) received a left-sided atrial Maze and 12.5% a bi-atrial Maze. The left atrial appendage was occluded in 72.1% cases. Overall, there were no significant differences between the two propensity matched groups in baseline demographics or intra-operative characteristics. Similarly, there were no significant differences in the post-operative short and mid-term outcomes between the two groups. There were no in-hospital or 30-day deaths. At the mid-term survival was similar between groups, log-rank test P=0.056. Maintenance of sinus rhythm at follow-up was 76%.

CONCLUSIONS

Mitral or double valve repair with concomitant cryoablation can be safely performed with either a MIMVS or RMV approach. Both methods demonstrated outstanding early and mid-term outcomes.

摘要

背景

心房颤动(AF)在二尖瓣疾病患者中频繁发生。此前已分别报道了与微创电视辅助(微创二尖瓣手术(MIMVS))或机器人辅助(RMV)二尖瓣手术同时进行的冷冻消融结果。然而,目前尚无关于这两种手术在安全性、有效性和中期随访方面进行比较的研究。

方法

2017年1月至2022年3月期间,294例患者在我院接受了MIMVS,187例患者接受了RMV。在使用22个术前变量进行1:1倾向评分匹配后,该研究纳入了104例患者。第1组(MIMVS)包括52例在2017 - 2022年期间采用微创电视辅助右侧小切口开胸手术的患者。第2组(RMV)包括52例在2019 - 2021年期间采用机器人辅助方法手术的患者。评估了早期和中期结果,包括窦性心律的维持情况。随访在中位随访2年时100%完成。

结果

对于整个倾向匹配队列,欧洲心脏手术风险评估系统(EuroSCORE)II中位数为3.14[四分位间距(IQR),1.93 - 4.99],中位年龄为68岁(IQR,61 - 74岁),三分之二的患者为男性。大多数(72.1%)接受了二尖瓣手术,26.9%进行了额外的三尖瓣手术。仅4例患者接受了二尖瓣置换术(3.8%)。大多数(87.5%)接受了左侧心房迷宫手术,12.5%接受了双心房迷宫手术。72.1%的病例闭塞了左心耳。总体而言,两个倾向匹配组在基线人口统计学或术中特征方面无显著差异。同样,两组术后短期和中期结果也无显著差异。无院内死亡或30天死亡。中期两组生存率相似,对数秩检验P = 0.056。随访时窦性心律维持率为76%。

结论

二尖瓣或双瓣膜修复同时进行冷冻消融,采用MIMVS或RMV方法均可安全实施。两种方法均显示出出色的早期和中期结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d363/10797378/3636d679b74c/jtd-15-12-6459-f1.jpg

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