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胎盘中的基因、表观遗传学与微小RNA调控

Genes, epigenetics and miRNA regulation in the placenta.

作者信息

Vaiman Daniel

机构信息

Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris-Descartes, 24, rue du Faubourg St-Jacques, 75014, Paris, France.

出版信息

Placenta. 2017 Apr;52:127-133. doi: 10.1016/j.placenta.2016.12.026. Epub 2016 Dec 25.

DOI:10.1016/j.placenta.2016.12.026
PMID:28043658
Abstract

This text reviews briefly the context in which epigenetics regulate gene expression in trophoblast development and function. It is an attempt to focus on a limited number of recent papers that, according to the author, shed new light on placental development, and constitute possible trails for improving knowledge and women follow-up in pathological pregnancies.

摘要

本文简要回顾了表观遗传学在滋养层细胞发育和功能中调控基因表达的背景。作者试图聚焦于近期的少数几篇论文,这些论文据作者认为为胎盘发育提供了新的见解,并为增进对病理妊娠的认识以及改善对孕妇的随访提供了可能的线索。

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