Chartier Caroline, Mofid Yassine, Bastard Cécile, Miette Véronique, Maruani Annabel, Machet Laurent, Ossant Frédéric
Université François-Rabelais de Tours, Inserm, Imagerie et Cerveau UMR U930, Tours, France.
Université François-Rabelais de Tours, Inserm, Imagerie et Cerveau UMR U930, Tours, France.
Ultrasound Med Biol. 2017 Mar;43(3):670-681. doi: 10.1016/j.ultrasmedbio.2016.11.007. Epub 2016 Dec 30.
Interest in elasticity estimation for thin layers is increasing because of the various potential applications, including dermatology and cosmetology. In this context, we propose a dedicated elastographic system using 1-D high-frequency transient elastography (HF-TE) to estimate the 1-D Young's modulus through the dermis and hypodermis, which are the two human skin layers of interest in this study. An experimental validation of the HF-TE method was first carried out on two homogeneous tissue-mimicking hard and soft phantoms. The Young's modulus values obtained in these phantoms were compared with those obtained by two complementary shear wave propagation techniques: shear wave-induced resonance elastography (SWIRE) and supersonic shear imaging (SSI). A third two-layer thin phantom, with mechanical properties similar to those of skin, was used to validate the ability of HF-TE to distinguish layers and measure elasticity. Finally, preliminary in vivo experiments conducted on forearm and cheek skin revealed the promising performance of HF-TE in measuring elasticity in the dermis and hypodermis.
由于包括皮肤病学和美容学在内的各种潜在应用，对薄层弹性估计的兴趣正在增加。在此背景下，我们提出了一种专用的弹性成像系统，该系统使用一维高频瞬态弹性成像（HF-TE）来估计穿过真皮和皮下组织的一维杨氏模量，这是本研究感兴趣的两层人体皮肤。首先在两个均匀的组织模拟硬体模体和软体模体上对HF-TE方法进行了实验验证。将在这些模体中获得的杨氏模量值与通过两种互补的剪切波传播技术获得的值进行比较：剪切波诱导共振弹性成像（SWIRE）和超音速剪切成像（SSI）。使用具有与皮肤相似机械性能的第三层双层薄模体来验证HF-TE区分层和测量弹性的能力。最后，在前臂和脸颊皮肤进行的初步体内实验表明，HF-TE在测量真皮和皮下组织的弹性方面具有良好的性能。
