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十二指肠肿瘤出血导致上消化道出血的罕见病例。

A Rare Case of Upper Digestive Hemorrhage due to Bleeding Duodenal Tumor.

作者信息

Turculeţ Claudiu, Ene Dragoş, Georgescu Teodor Florin, Ciucă E, Vlădăşcău A, Iordache Florin, Beuran Mircea

出版信息

Chirurgia (Bucur). 2016 Nov-Dec;111(6):505-508. doi: 10.21614/chirurgia.111.6.505.

Abstract

We present the case of a 48-year-old patient with no medical history, who presents himself to the emergency room with melena, asthenia and dizziness. The blood tests revealed a severe anemia (Hb = 4,8 g/dL). He is admitted in the Gastroenterology ward, where a first superior digestive endoscopy is performed which shows a duodenal bleeding tumor (second duodenum) of 7 cm in length. After the administration of red blood cell mass, plasma and haemostatic agents the level of the hemoglobin increases. The abdominal CT scan reveals a 3/5 tumor localized in the second and third duodenum. The superior digestive endoscopy is repeated and haemostasis of the bleeding tumor is accomplished. The surgical exploration of the peritoneal cavity discovered a partial stenosing, ulcerated duodenal tumor (third and fourth duodenum) and duodenectomy (third and fourth duodenum), segmental enterectomy (first loop of the jejunum), end to end duodeno-jejunal anastomosis, transgastric closure of the pylorus, gastro-enteric anastomosis on Omega loop with Braun fistula were performed, after the result of the extemporaneous histopathological exam suggested a GIST tumor. The postoperative evolution was favorable. The histopathological exam diagnosed the duodenal tumor as a gastrointestinal stromal tumor (GIST) with tumor free resection margins. The particularity of this case is the rare etiology of the upper gastrointestinal hemorrhage and its severity.

摘要

我们报告一例48岁无病史患者,其因黑便、乏力和头晕前往急诊室就诊。血液检查显示严重贫血(血红蛋白=4.8g/dL)。他被收入胃肠病科病房,在那里进行了首次上消化道内镜检查,发现一个长7厘米的十二指肠出血性肿瘤(十二指肠第二段)。输注红细胞悬液、血浆及止血药物后,血红蛋白水平升高。腹部CT扫描显示一个3/5大小的肿瘤位于十二指肠第二和第三段。再次进行上消化道内镜检查并实现了出血肿瘤的止血。对腹腔进行手术探查发现一个部分狭窄、溃疡的十二指肠肿瘤(十二指肠第三和第四段),遂行十二指肠切除术(十二指肠第三和第四段)、节段性肠切除术(空肠第一段)、十二指肠空肠端端吻合术、经胃幽门关闭术、Omega袢胃肠吻合术加布劳恩吻合术,术中组织病理学检查结果提示为胃肠道间质瘤(GIST)。术后病情进展顺利。组织病理学检查诊断十二指肠肿瘤为胃肠道间质瘤(GIST),切缘无肿瘤残留。该病例的特殊性在于上消化道出血病因罕见且病情严重。

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