Kuni D R, Silvay G
American Antec Inc., Valencia, California 91355.
Biomed Instrum Technol. 1989 Sep-Oct;23(5):388-95.
Until recently, there has been no simple, accurate, reliable technique for monitoring depth of anesthesia during surgery. A system that measures lower esophageal contractility (LEC) has been designed for this purpose. The system consists of a monitor and a disposable esophageal probe equipped with provoking and measuring balloons. Since the motor control of the esophagus is directly controlled by the brain stem, LEC was postulated to be a reflection of the anesthetic state of the patient. Multiple-center clinical studies have shown that LEC correlates significantly (p less than 0.005) with concentrations of volatile anesthetic agents and patient responses to surgical stimulation. Closed-loop anesthetic techniques have been developed at several institutions based on LEC and hemodynamic parameters. Lower esophageal contractility has been shown to be an accurate monitor of anesthetic depth for a variety of surgical procedures and anesthetic techniques.
直到最近，还没有一种简单、准确、可靠的技术用于监测手术期间的麻醉深度。为此设计了一种测量下食管收缩性（LEC）的系统。该系统由一台监测仪和一个配备激发球囊和测量球囊的一次性食管探头组成。由于食管的运动控制直接受脑干控制，因此推测LEC可反映患者的麻醉状态。多中心临床研究表明，LEC与挥发性麻醉剂浓度及患者对手术刺激的反应显著相关（p小于0.005）。基于LEC和血流动力学参数，多家机构已开发出闭环麻醉技术。下食管收缩性已被证明是各种外科手术和麻醉技术中麻醉深度的准确监测指标。
