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顺行入路失败后,经逆行入路成功进行血管内治疗对严重肢体缺血患者膝下慢性完全闭塞病变的长期疗效

Long-Term Outcomes of Successful Endovascular Therapy Via the Retrograde Approach for Below-the-Knee Chronic Total Occlusion in Patients With Critical Limb Ischemia After a Failed Antegrade Approach.

作者信息

Matsumi Junya, Takada Takuma, Moriyama Noriaki, Ochiai Tomoki, Tobita Kazuki, Shishido Koki, Sugitatsu Kazuya, Mizuno Shingo, Yamanaka Futoshi, Murakami Masato, Tanaka Yutaka, Takahashi Saeko, Akasaka Takeshi, Saito Shigeru

机构信息

Department of Cardiology, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, Kanagawa 247- 0072, Japan.

出版信息

J Invasive Cardiol. 2017 Jan;29(1):2-8.

Abstract

OBJECTIVE

This study evaluated long-term results following successful endovascular therapy (EVT) for chronic total occlusion (CTO) below the knee (BTK) using the retrograde approach after a failed antegrade approach.

METHODS

Nineteen patients (19 limbs) with critical limb ischemia (CLI) who underwent successful EVT for BTK-CTO using the retrograde approach after a failed antegrade approach during 2010-2014 were studied.

RESULTS

Mean duration of the follow-up period was 25.5 ± 17.9 months, and mean age was 76.0 ± 8.6 years. Patients on hemodialysis accounted for 10 cases (52.6%). Patients with Rutherford class 4 constituted 3 cases (15.8%) , while 8 patients each (42.1%) were categorized as Rutherford class 5 and class 6, respectively. All lesions were de novo CTOs. The mean occlusion length was 203.7 ± 114.7 mm. Vascular access for the retrograde approach was obtained via distal puncture in 9 cases (47.4%), whereas the transcollateral approach was employed in 10 cases (52.6%). The amputation-free survival rates at 1, 2, 3, 4, and 5 years after the index procedure were 78.6%, 66.9%, 66.9%, 50.2%, and 50.2%, respectively.

CONCLUSION

Successful EVT for BTK-CTO using various techniques via the retrograde approach provides promising long-term results in patients with CLI.

摘要

目的

本研究评估了在顺行入路失败后采用逆行入路对膝下慢性完全闭塞(CTO)进行成功血管内治疗(EVT)后的长期结果。

方法

对2010年至2014年间19例(19条肢体)因肢体严重缺血(CLI)在顺行入路失败后采用逆行入路成功进行膝下CTO-EVT的患者进行了研究。

结果

随访期平均时长为25.5±17.9个月,平均年龄为76.0±8.6岁。接受血液透析的患者有10例(52.6%)。卢瑟福分级4级的患者有3例(15.8%),而卢瑟福分级5级和6级的患者各有8例(分别占42.1%)。所有病变均为原发性CTO。平均闭塞长度为203.7±114.7毫米。逆行入路的血管通路通过远端穿刺获得9例(47.4%),而采用经侧支入路的有10例(52.6%)。首次手术后1、2、3、4和5年的无截肢生存率分别为78.6%、66.9%、66.9%、50.2%和50.2%。

结论

通过逆行入路采用各种技术对膝下CTO进行成功的EVT,为CLI患者提供了有前景的长期结果。

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