Chan P, Lan C K, Wan Y L
Changgeng Yi Xue Za Zhi. 1989 Jun 20;12(2):115-20.
From August 1986 to October 1987, there were 5 cases of primary mycotic aneurysm of the lower abdominal aorta in Chang Gung Memorial Hospital at Kaoshiung. All patients were proved to have Salmonella cholerasuis (Sal. chol.) septicemia by blood culture. The ages ranged from 60 to 80 years old, the mean age was 71.6 years old. The male to female ratio was 4 to 1, 3 patients had diabetes mellitus (DM) and 3 had hypertension. The duration of symptoms lasted from 1 week to 2 months before diagnosis. Clinically, all patients had sepsis with fever, chills, leucocytosis, and complained of pain in the lower abdomen (80%), at flank (20%) or low back (20%). Abdominal tenderness was present in 3 (60%). Two patients underwent surgery, 1 expired during the operation, the other expired 1 month after operation because of retroperitoneal abscess and sepsis. Three were discharged in septic shock and expired within 1 day. The mortality rate was 100%. The diagnosis of complicated aneurysm of the lower abdominal aorta was established in all by computed tomography (CT). In conclusion, when there are clinical manifestations of sepsis, positive blood culture for Sal. chol., and pain or tenderness in the lower abdomen, flank area or back, one should consider the possibility of mycotic aneurysm of the lower abdominal aorta. Although the prognosis is poor, early surgical intervention may improve the outcome. And the diagnosis is best established by CT.
1986年8月至1987年10月,高雄长庚纪念医院共收治5例腹主动脉原发性霉菌性动脉瘤患者。所有患者血培养均证实为猪霍乱沙门氏菌败血症。年龄范围为60至80岁,平均年龄71.6岁。男女比例为4比1,3例患者患有糖尿病,3例患有高血压。症状持续时间从1周到2个月不等,直到确诊。临床上,所有患者均有败血症,伴有发热、寒战、白细胞增多,并主诉下腹部疼痛(80%)、胁腹疼痛(20%)或下背部疼痛(20%)。3例(60%)有腹部压痛。2例患者接受了手术,1例在手术中死亡,另1例术后1个月因腹膜后脓肿和败血症死亡。3例因感染性休克出院,1天内死亡。死亡率为100%。所有患者均通过计算机断层扫描(CT)确诊为腹主动脉复杂性动脉瘤。总之,当出现败血症的临床表现、猪霍乱沙门氏菌血培养阳性以及下腹部、胁腹或背部疼痛或压痛时,应考虑腹主动脉霉菌性动脉瘤的可能性。尽管预后较差,但早期手术干预可能改善结局。最佳诊断方法是CT。