Law K L, Lin H Y, Chi C S
Zhonghua Yi Xue Za Zhi (Taipei). 1989 Apr;43(4):273-6.
Cerebrospinal fluid eosinophilia are an uncommon finding that is most often the result of a helminthic infection of the central nervous system. Information from the recorded literature suggests the differential diagnosis of this clinical observation is relatively limited. This is a report of a girl with acute lymphoblastic leukemia who developed central nervous system relapse of leukemia following 3 years of remission. She showed marked eosinophilia in the cerebrospinal fluid 6 weeks preceding central nervous system leukemia. No cause for the eosinophilia was identified. The gradual accumulation of case reports of eosinophilia in the cerebrospinal fluid with or without blood eosinophilia in patient with leukemia suggests that this finding is of some importance.
脑脊液嗜酸性粒细胞增多是一种不常见的表现，最常见于中枢神经系统的蠕虫感染。文献记载的信息表明，这一临床观察结果的鉴别诊断相对有限。本文报告一名患急性淋巴细胞白血病的女孩，在缓解3年后发生白血病中枢神经系统复发。在中枢神经系统白血病出现前6周，她的脑脊液中出现明显的嗜酸性粒细胞增多。未发现嗜酸性粒细胞增多的原因。白血病患者脑脊液中出现嗜酸性粒细胞增多（无论有无血液嗜酸性粒细胞增多）的病例报告逐渐增多，提示这一发现具有一定重要性。
