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不列颠哥伦比亚省对ProHIBit疫苗不良反应的上市后监测。

Postmarketing surveillance of adverse reactions to ProHIBit vaccine in British Columbia.

出版信息

CMAJ. 1989 Nov 1;141(9):927-9.

PMID:2804851
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1451440/
Abstract

Prohibit was well tolerated by the children. The reactions at the injection site were generally minor, and the systemic symptoms were usually mild. For only 12 of the children had medical attention been sought for local or systemic symptoms; none required hospital admission. Although invasive Hib infection developed in one subject; the observed rate was consistent with the expected rate of Hib disease.

摘要

儿童对Prohibit耐受性良好。注射部位的反应通常较小,全身症状通常较轻。只有12名儿童因局部或全身症状就医;无人需要住院治疗。尽管有一名受试者发生侵袭性b型流感嗜血杆菌感染;观察到的发病率与预期的b型流感嗜血杆菌疾病发病率一致。

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本文引用的文献

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Haemophilus b polysaccharide vaccine: need for continuing assessment.b型流感嗜血杆菌多糖疫苗:持续评估的必要性。
Pediatr Infect Dis J. 1987 Aug;6(8):701-3. doi: 10.1097/00006454-198708000-00001.