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酒精性脊髓病与营养缺乏症

Alcoholic Myelopathy and Nutritional Deficiency.

作者信息

Koike Haruki, Nakamura Tomohiko, Ikeda Shohei, Takahashi Mie, Kawagashira Yuichi, Iijima Masahiro, Katsuno Masahisa, Sobue Gen

机构信息

Department of Neurology, Nagoya University Graduate School of Medicine, Japan.

出版信息

Intern Med. 2017;56(1):105-108. doi: 10.2169/internalmedicine.56.7364. Epub 2017 Jan 1.

Abstract

A patient with chronic alcoholism presented with myelopathy and low serum folate and cobalamin levels. A 42-year-old alcoholic man had gait disturbance for 4 months. A neurological examination revealed marked spasticity with increased deep tendon reflexes and extensor plantar responses of the lower limbs. His cobalamin level was decreased and his serum folate level was particularly low. His plasma ammonia level was not increased. Abstinence and folic acid and cobalamin supplementation stopped the progression of his neurological deficits. This case indicates that nutritional deficiency should be monitored closely in patients with chronic alcoholism who present with myelopathy.

摘要

一名慢性酒精中毒患者出现脊髓病,血清叶酸和钴胺素水平较低。一名42岁的酗酒男性有4个月的步态障碍。神经系统检查显示明显的痉挛,下肢深腱反射增强和跖伸反应。他的钴胺素水平降低,血清叶酸水平特别低。他的血浆氨水平没有升高。戒酒以及补充叶酸和钴胺素阻止了他神经功能缺损的进展。该病例表明,对于出现脊髓病的慢性酒精中毒患者,应密切监测营养缺乏情况。

相似文献

1
Alcoholic Myelopathy and Nutritional Deficiency.酒精性脊髓病与营养缺乏症
Intern Med. 2017;56(1):105-108. doi: 10.2169/internalmedicine.56.7364. Epub 2017 Jan 1.
2
Slowly progressive folate-deficiency myelopathy: report of a case.
J Neurol Sci. 2014 Jan 15;336(1-2):273-5. doi: 10.1016/j.jns.2013.10.032. Epub 2013 Oct 30.

本文引用的文献

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Clinicopathologic features of folate-deficiency neuropathy.叶酸缺乏性神经病的临床病理特征。
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Spinal cord involvement in patients with cirrhosis.肝硬化患者的脊髓受累情况。
World J Gastroenterol. 2014 Mar 14;20(10):2578-85. doi: 10.3748/wjg.v20.i10.2578.
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Neurologic aspects of cobalamin (B12) deficiency.钴胺素(维生素B12)缺乏的神经学方面
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Slowly progressive folate-deficiency myelopathy: report of a case.
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