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非包膜型流感嗜血杆菌引起的脑脊液分流感染

Cerebrospinal fluid shunt infections by unencapsulated Haemophilus influenzae.

作者信息

Hellbusch L C, Penn R G

机构信息

Department of Surgery (Neurosurgery), Children's Memorial Hospital, Omaha, NE 68114.

出版信息

Childs Nerv Syst. 1989 Oct;5(5):315-7. doi: 10.1007/BF00274521.

DOI:10.1007/BF00274521
PMID:2805003
Abstract

Three cases of cerebrospinal fluid (CSF) shunt infection by unencapsulated Haemophilus influenzae are presented. In all, 22 cases of H. influenzae CSF shunt infections have previously been reported. In contrast to these cases, the current three patients showed acute involvement of the peritoneal end of the shunt with unencapsulated H. influenzae. Medical therapy without shunt removal is successful in eliminating H. influenzae type b shunt infection associated with meningitis. However, significant involvement of the peritoneal portion of the catheter by unencapsulated H. influenzae is an indication for removal of the distal portion of the catheter along with appropriate antibiotic therapy.

摘要

本文报告了3例由未分型流感嗜血杆菌引起的脑脊液(CSF)分流感染病例。此前总共已报告过22例流感嗜血杆菌引起的CSF分流感染病例。与这些病例不同的是,目前这3例患者的分流装置腹腔端出现了未分型流感嗜血杆菌的急性感染。对于与脑膜炎相关的b型流感嗜血杆菌分流感染,不拆除分流装置进行药物治疗可成功消除感染。然而,未分型流感嗜血杆菌对导管腹腔部分造成严重感染时,则表明需要拆除导管远端部分并进行适当的抗生素治疗。

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Invasive disease due to nontypeable Haemophilus influenzae among children in Arkansas.阿肯色州儿童中由不可分型流感嗜血杆菌引起的侵袭性疾病
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本文引用的文献

1
Ventriculoperitoneal shunt-associated infection due to Haemophilus influenzae.
Pediatrics. 1980 May;65(5):1007-9.
2
Haemophilus influenzae infections of cerebrospinal fluid shunts. Report of two cases.脑脊液分流管的流感嗜血杆菌感染。两例报告。
J Neurosurg. 1981 Feb;54(2):261-3. doi: 10.3171/jns.1981.54.2.0261.
3
Treatment of Haemophilus influenzae type b meningitis in children with cerebrospinal fluid shunts.
J Pediatr. 1980 Sep;97(3):424-6. doi: 10.1016/s0022-3476(80)80194-6.
4
Antibiotic resistance in Haemophilus influenzae.流感嗜血杆菌中的抗生素耐药性。
Pediatr Infect Dis. 1983 Sep-Oct;2(5):352-5. doi: 10.1097/00006454-198309000-00003.
5
Haemophilus influenzae meningitis in the presence of a cerebrospinal fluid shunt.
Neurosurgery. 1986 Jan;18(1):79-81. doi: 10.1227/00006123-198601000-00013.
6
Cerebrospinal fluid shunt infections: a personal view.脑脊液分流感染:个人观点
Pediatr Infect Dis. 1985 Mar-Apr;4(2):113-8. doi: 10.1097/00006454-198503000-00001.
7
Treatment of infections of cerebrospinal fluid shunts.
Rev Infect Dis. 1987 May-Jun;9(3):595-603. doi: 10.1093/clinids/9.3.595.
8
Haemophilus influenzae meningitis in the presence of cerebrospinal fluid shunts.
Childs Nerv Syst. 1988 Jun;4(3):164-5. doi: 10.1007/BF00270910.
9
Gram-negative cerebrospinal fluid shunt-associated infections.
Pediatrics. 1977 Apr;59(4):614-8.