Joy J, Kartha C C, Balakrishnan K G
Department of Cardiology and Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
Cardiology. 1989;76(4):249-54. doi: 10.1159/000174500.
Mitral valve specimens from 9 patients with severe mitral regurgitation due to mitral valve prolapse were examined. All belonged to the age group 10-30 years and had rapid progression of their illness, requiring early surgery. The histopathological examination of valve tissue revealed varying degrees of fibrosis, increased vascularity and absence of myxomatous degeneration. These patients may represent a distinct group of mitral valve prolapse, whose clinical course is different from those with typical myxomatous degeneration of the mitral valve.
对9例因二尖瓣脱垂导致严重二尖瓣反流患者的二尖瓣标本进行了检查。所有患者年龄在10至30岁之间，病情进展迅速，需要早期手术。瓣膜组织的组织病理学检查显示有不同程度的纤维化、血管增多以及无黏液样变性。这些患者可能代表了二尖瓣脱垂的一个独特群体，其临床病程与典型二尖瓣黏液样变性患者不同。
