Vashistha Nitin, Singhal Dinesh, Makkar Gurpreet, Chakravarty Suneel, Raj Vivek
Department of Surgical Gastroenterology, Max Super Speciality Hospital, Saket, New Delhi 110017, India.
Department of Radiology, Max Super Speciality Hospital, Saket, New Delhi 110017, India.
Case Rep Surg. 2016;2016:4681989. doi: 10.1155/2016/4681989. Epub 2016 Dec 6.
Giant gastric ulcer (GGU) is defined as an ulcer more than 3 cm in diameter. Now infrequent in clinical practice, in the pre-H2 receptor antagonist (H2RA) era, the incidence of GGU varied between 12 and 24% of all gastric ulcers. Proton pump inhibitors reportedly achieve better healing rates and symptom relief in comparison to H2RA. The GGU is associated with high incidence of serious complications such as hemorrhage. A perforated GGU though rare (<2%) offers serious challenges in management. We report one such case wherein the role of multidetector CT scan (MDCT) for diagnosis and treatment planning, surgical options for GGU perforations, and factors affecting outcome are discussed.
巨大胃溃疡(GGU)被定义为直径超过3厘米的溃疡。在临床实践中,这种情况现在并不常见,在H2受体拮抗剂(H2RA)时代之前,GGU在所有胃溃疡中的发病率在12%至24%之间。据报道,与H2RA相比,质子泵抑制剂能达到更好的愈合率和症状缓解效果。GGU与诸如出血等严重并发症的高发生率相关。虽然穿孔性GGU很少见(<2%),但在治疗上具有严峻挑战。我们报告了这样一个病例,其中讨论了多排螺旋CT扫描(MDCT)在诊断和治疗规划中的作用、GGU穿孔的手术选择以及影响预后的因素。