Zhang C Y, Wang T G
Zhonghua Liu Xing Bing Xue Za Zhi. 1989 Aug;10(4):235-7.
A case-control study was conducted among 150 woman suffered from endometrial cancer (EC) in Beijing from 1982.1.1-1985.12.31 and matched with two controls from the neighbourhood to explore the risk factors for EC. The data were analysed with X2 test and Linear Logistic Regression. Result of the study are listed. The risk factors directly related to EC might be obesity, nulliparity and low parity, early menarche, liver diseases. The risk factors indirectly related to EC might be irregular menstruation, premenstrual tension, dysfunctional uterine bleeding. The oral combined contraceptives showed a protective effect on EC. The results of the study support the EC etiology hypothesis of 'unopposed action of estrogen'.
1982年1月1日至1985年12月31日期间，在北京对150名子宫内膜癌（EC）女性患者进行了一项病例对照研究，并与来自邻里的两名对照进行匹配，以探讨EC的危险因素。数据采用X2检验和线性逻辑回归进行分析。研究结果如下。与EC直接相关的危险因素可能是肥胖、未生育和低生育、初潮早、肝脏疾病。与EC间接相关的危险因素可能是月经不调、经前紧张、功能性子宫出血。口服复方避孕药对EC有保护作用。该研究结果支持“雌激素无对抗作用”的EC病因假说。
