Phelps Andrea J, Varker Tracey, Metcalf Olivia, Dell Lisa
Phoenix Australia-Centre for Posttraumatic Mental Health, Department of Psychiatry, University of Melbourne, Level 3, Alan Gilbert Building, 161 Barry Street, Carlton, Victoria, Australia 3053.
Mil Med. 2017 Jan;182(1):e1541-e1550. doi: 10.7205/MILMED-D-16-00010.
Insomnia and related sleep disturbances commonly occur in veterans, with prevalence rates as high as 90% reported in some studies. Military-specific factors such as sleep disturbances during military training and deployment, as well as a higher prevalence of post-traumatic stress disorder (PTSD), which is known to poorly impact sleep, may contribute to higher insomnia rates in veterans. Although evidence-based guidelines for the treatment of insomnia exist, the unique nature of veterans sleep problems means they may differ in their response to treatment. The aim of this study was to review the evidence for interventions for veterans with sleep disturbances.
This literature review used a rapid evidence assessment methodology, also known as rapid review. The rapid evidence assessment methodology involves rigorously locating, appraising, and synthesising the evidence while making concessions to the breadth or the depth of the process in order to significantly decrease the length of the process. EMBASE, MEDLINE (PubMed), PsychINFO, Cochrane, Clinical Guidelines Portal (Australia), and the National Guideline Clearinghouse (United States) were searched for peer-reviewed literature and guidelines published from 2004 to August 2015 that investigated psychological interventions for veterans with sleep disturbances. The literature was assessed in terms of strength (quality, quantity, and level of evidence), direction, and the consistency, generalizability, and applicability of the findings to the population of interest. These assessments were then collated to determine an overall ranking of level of support for each intervention: "Supported" (clear, consistent evidence of a beneficial effect), "Promising" (evidence suggestive of a beneficial effect but further research is required), "Unknown" (insufficient evidence of beneficial effect and further research is required), and "Not Supported" (clear consistent evidence of no effect or negative harmful effect).
From an initial yield of 1,131 articles, 18 studies met the inclusion criteria for review. The majority of the studies investigated the effectiveness of cognitive behavioral therapy for insomnia (CBTi; n = 10). Five studies investigated CBTi with an adjunctive psychotherapy, typically for PTSD-related sleep disturbances. One further study investigated sleep hygiene education (a component of CBTi) with pharmacotherapy. Two final studies investigated hypnotherapy and mind-body bridging, respectively. Overall, the quality of the studies was mixed, with some high and some poor quality studies.
There was sufficient evidence to support CBTi with adjunctive psychotherapy for veterans with PTSD-related sleep disturbances, although the evidence for CBTi in the treatment of general sleep disturbance for veterans was ranked as "promising." This indicates a beneficial effect, but more research is needed to confidently establish efficacy in a veteran population. There is currently insufficient evidence to support the use of sleep hygiene education and pharmacotherapy, hypnotherapy, or mind-body bridging. Further research dismantling the components of CBTi is needed to identify which are the critical components. Such research has the potential to lead to brief, targeted, and accessible treatments that overcome the time and stigma-related barriers to care that veterans often face.
失眠及相关睡眠障碍在退伍军人中普遍存在,一些研究报告的患病率高达90%。军事训练和部署期间的睡眠障碍等军事特定因素,以及创伤后应激障碍(PTSD)的较高患病率(已知其对睡眠有不良影响),可能导致退伍军人失眠率更高。尽管存在基于证据的失眠治疗指南,但退伍军人睡眠问题的独特性质意味着他们对治疗的反应可能不同。本研究的目的是回顾针对有睡眠障碍的退伍军人的干预措施的证据。
本系统评价采用快速证据评估方法,也称为快速综述。快速证据评估方法包括严格地查找、评估和综合证据,同时在过程的广度或深度上做出让步,以显著缩短过程长度。检索了EMBASE、MEDLINE(PubMed)、PsychINFO、Cochrane、临床指南门户(澳大利亚)和国家指南交换中心(美国),以查找2004年至2015年8月发表的关于对有睡眠障碍的退伍军人进行心理干预的同行评审文献和指南。根据强度(质量、数量和证据水平)、方向以及研究结果对目标人群的一致性、普遍性和适用性对文献进行评估。然后对这些评估进行整理,以确定每种干预措施支持水平的总体排名:“支持”(有明确、一致的有益效果证据)、“有前景”(有暗示有益效果的证据,但需要进一步研究)、“未知”(有益效果证据不足,需要进一步研究)和“不支持”(有明确、一致的无效果或负面有害效果证据)。
从最初的1131篇文章中,有18项研究符合纳入综述的标准。大多数研究调查了失眠认知行为疗法(CBTi;n = 10)的有效性。五项研究调查了CBTi联合辅助心理治疗,通常用于治疗与PTSD相关的睡眠障碍。另一项研究调查了睡眠卫生教育(CBTi的一个组成部分)联合药物治疗。最后两项研究分别调查了催眠疗法和身心联结疗法。总体而言,研究质量参差不齐,有一些高质量研究,也有一些低质量研究。
有足够的证据支持CBTi联合辅助心理治疗用于治疗与PTSD相关睡眠障碍的退伍军人,尽管CBTi治疗退伍军人一般睡眠障碍的证据被列为“有前景”。这表明有有益效果,但需要更多研究才能确定在退伍军人人群中的疗效。目前没有足够的证据支持使用睡眠卫生教育、药物治疗、催眠疗法或身心联结疗法。需要进一步研究剖析CBTi的组成部分,以确定哪些是关键组成部分。此类研究有可能带来简短、有针对性且易于获得的治疗方法,克服退伍军人经常面临的时间和与耻辱感相关的护理障碍。