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瑞士HIV队列研究患者中身体活动不足的高患病率。

High prevalence of physical inactivity among patients from the Swiss HIV Cohort Study.

作者信息

Schäfer Juliane, Young Jim, Calmy Alexandra, Nicca Dunja, Hasse Barbara, Brun Del Re Claudia, Cavassini Matthias, Bernasconi Enos, Schmidt-Trucksäss Arno, Bucher Heiner C

机构信息

a Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, University of Basel , Basel , Switzerland.

b Department of Sport, Exercise and Health, Sports and Exercise Medicine , University of Basel , Basel , Switzerland.

出版信息

AIDS Care. 2017 Aug;29(8):1056-1061. doi: 10.1080/09540121.2016.1274016. Epub 2017 Jan 5.

DOI:10.1080/09540121.2016.1274016
PMID:28052699
Abstract

Physical activity (PA) can improve cardiorespiratory status, strength, body composition and quality of life for patients infected with HIV. Evidence from HIV-uninfected populations also shows that PA is associated with a lower risk of mortality, primarily death due to cardiovascular causes. There is, however, a lack of data on how physically active HIV-infected patients are. In this study, we assessed levels of self-reported PA over time in patients enrolled in the Swiss HIV Cohort Study, a large multicentre prospective observational cohort study. We included a total of 10,540 patients who completed at least one report of PA between December 2009 and November 2014 during routine clinical follow-up (scheduled every 6 months). In the first year after December 2009 there was a higher rate of non-response so these data are of a lesser reliability. Over the next four years, the percentage of patients reporting no free-time PA at all declined from 49% to 44%. In contrast, in two "Sport Switzerland" surveys of the general population in 2008 and 2014, the percentage of individuals reporting no sports activities at all was considerably lower and relatively stable over time (27% in 2008; 26% in 2014). In our analysis, the percentage of patients reporting sedentary activity at work increased from 23% to 26% over the four years. Subgroup findings suggest differences between women and men and between patients classified by their age, stage of infection and CD4 cell count. Integrating PA counselling into the routine care of HIV-infected patients and promoting PA among this population has the potential to improve the general state of health and quality of life for HIV-infected patients and reduce their risk of cardiovascular disease.

摘要

体育活动(PA)可以改善感染艾滋病毒患者的心肺功能、力量、身体成分和生活质量。来自未感染艾滋病毒人群的证据还表明,体育活动与较低的死亡风险相关,主要是心血管疾病导致的死亡。然而,目前缺乏关于感染艾滋病毒的患者体育活动情况的数据。在本研究中,我们评估了参与瑞士艾滋病毒队列研究(一项大型多中心前瞻性观察队列研究)的患者随时间自我报告的体育活动水平。我们纳入了总共10540名患者,他们在2009年12月至2014年11月的常规临床随访(每6个月安排一次)期间至少完成了一份体育活动报告。2009年12月后的第一年,无应答率较高,因此这些数据的可靠性较低。在接下来的四年里,完全不进行休闲体育活动的患者百分比从49%下降到了44%。相比之下,在2008年和2014年对普通人群进行的两项“瑞士体育”调查中,完全不进行体育活动的个体百分比要低得多,并且随时间相对稳定(2008年为27%;2014年为26%)。在我们的分析中,报告工作时久坐不动的患者百分比在这四年中从23%增加到了26%。亚组研究结果表明,女性和男性之间以及按年龄、感染阶段和CD4细胞计数分类的患者之间存在差异。将体育活动咨询纳入艾滋病毒感染患者的常规护理,并在这一人群中推广体育活动,有可能改善艾滋病毒感染患者的总体健康状况和生活质量,并降低他们患心血管疾病的风险。

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