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髂骨翼高分化脂肪肉瘤的多发性脊柱转移:病例报告

Multiple spinal metastases from a well-differentiated liposarcoma of the iliac wing: a case report.

作者信息

Ben Nsir A, Boubaker A, Kassar A Z, Abderrahmen K, Kchir N, Jemel H

机构信息

Neurological Surgery Department, Fattouma Bourguiba University Hospital , Monastir, Tunisia.

Neurological Surgery Department, Tunisian National Institute of Neurology, Faculty of Medicine of Tunis, University of Tunis El Manar , Tunis, Tunisia.

出版信息

Spinal Cord Ser Cases. 2015 Jul 9;1:15007. doi: 10.1038/scsandc.2015.7. eCollection 2015.

Abstract

STUDY DESIGN

A case report.

OBJECTIVES

To report an unusual case of multiple spinal metastases from an undiagnosed well-differentiated liposarcoma (WDLPS) of the iliac wing and to stress the need of a meticulous clinical examination and further screening of patients with chronic and asymptomatic bony lesions.

SETTING

University of medicine of Monastir, Department of neurological surgery, Fattouma Bourguiba University Hospital, Monastir, Tunisia and University of Medicine of Tunis EL Manar, Department of neurological surgery, Tunisian National Institute of Neurology, Tunis, Tunisia.

METHODS

A 39-year-old man presented with signs of spinal cord compression for the past 2 weeks. His medical history was consistent for an asymptomatic right iliac wing mass that appeared 3 years ago and for which he has not consulted. Magnetic resonance imaging revealed multiple bony lesions of the thoraco-lumbar spine associated with a 6-cm right paravertebral mass at the T4 level extending posteriorly through the intervertebral foramina to the spinal canal causing major spinal cord compression. An emergent T2-T6 laminectomy allowed for a complete resection of the epidural mass. Pathological examination confirmed the diagnosis of well-differentiated liposarcoma. Adjunctive radiation therapy was administered.

RESULTS

The patient's neurological status improved remarkably under an intensive care and rehabilitation program. He was ambulatory without assistance in the second postoperative week.

CONCLUSION

The case reported in this paper represents a genuine example of the possible metastatic potential of WDLPSs of the bone and underscores the importance of examining patients thoroughly, especially when they have chronic and asymptomatic lesions.

摘要

研究设计

病例报告。

目的

报告一例罕见的髂骨翼未确诊的高分化脂肪肉瘤(WDLPS)发生多处脊柱转移的病例,并强调对慢性无症状骨病变患者进行细致临床检查及进一步筛查的必要性。

背景

突尼斯莫纳斯提尔医学大学、莫纳斯提尔法图玛·布尔吉巴大学医院神经外科;突尼斯突尼斯城曼纳尔大学医学系、突尼斯国家神经病学研究所神经外科。

方法

一名39岁男性在过去2周出现脊髓压迫症状。他有3年前出现的无症状右髂骨翼肿块病史,且未就医。磁共振成像显示胸腰椎多处骨病变,T4水平右侧椎旁有一个6厘米的肿块,向后通过椎间孔延伸至椎管,导致严重脊髓压迫。急诊行T2 - T6椎板切除术,完整切除硬膜外肿块。病理检查确诊为高分化脂肪肉瘤。给予辅助放疗。

结果

在重症监护和康复计划下,患者神经状态显著改善。术后第二周他可独立行走。

结论

本文报告的病例是骨WDLPS可能具有转移潜能的真实例证,强调了全面检查患者的重要性,尤其是当他们有慢性无症状病变时。

相似文献

本文引用的文献

1
Liposarcoma: a soft tissue tumor with many presentations.脂肪肉瘤:一种具有多种表现形式的软组织肿瘤。
Musculoskelet Surg. 2014 Dec;98(3):171-7. doi: 10.1007/s12306-014-0332-1. Epub 2014 Jul 22.
2
Liposarcomas.脂肪肉瘤。
Hematol Oncol Clin North Am. 2013 Oct;27(5):939-55. doi: 10.1016/j.hoc.2013.07.010.
4
Why do patients with low-grade soft tissue sarcoma die?低度恶性软组织肉瘤患者为何会死亡?
Ann Surg Oncol. 2008 Dec;15(12):3550-60. doi: 10.1245/s10434-008-0163-0. Epub 2008 Oct 1.
10
Primary liposarcoma of the thoracic spine: case report.胸椎原发性脂肪肉瘤:病例报告
Eur Spine J. 2005 Aug;14(6):613-8. doi: 10.1007/s00586-004-0866-2. Epub 2005 Apr 30.

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