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夏科氏脊柱关节病:脊髓损伤后日益常见的远期并发症,且治疗方法尚无定论。

Charcot spinal arthropathy: an increasing long-term sequel after spinal cord injury with no straightforward management.

作者信息

Grassner Lukas, Geuther Martina, Mach Orpheus, Bühren Volker, Vastmans Jan, Maier Doris

机构信息

Center for Spinal Cord Injuries, Trauma Center Murnau, Bavaria, Germany; Institute of Molecular Regenerative Medicine, SCI-TReCS (Spinal Cord Injury and Tissue Regeneration Center Salzburg), Paracelsus Medical University, Salzburg, Austria.

Center for Spinal Cord Injuries, Trauma Center Murnau , Bavaria, Germany.

出版信息

Spinal Cord Ser Cases. 2015 Oct 8;1:15022. doi: 10.1038/scsandc.2015.22. eCollection 2015.

Abstract

Charcot spinal arthropathy (CSA) is most likely increasing in patients suffering from consequences of spinal cord injury. We want to highlight initial symptoms, certain risk factors and perioperative complications of this condition. A single center retrospective case series in a specialized Center for Spinal Cord Injuries, BG Trauma Center Murnau, Germany highlighting the potential obstacles in the management of Charcot spine. We describe four female paraplegic patients (mean age: 50.75 years; range: 42-67), who developed Charcot spinal arthropathies. The mean age at the time of the accident was 21.5 years (3-35), the time lag after the accident before CSA was developed and finally diagnosed was on average 29.5 years (17-39) and the mean follow-up period was 39.5 months (6-73). Patient histories, initial symptoms, risk factors as well as the management and postoperative complications are provided. Charcot spine is an important potential sequel of spinal cord injury, which can lead to significant disability and spinal emergencies in affected individuals. More studies are needed to provide better recommendations for spine surgeons. Conservative treatment is an option. Posterior fixation alone does not seem to be sufficient.

摘要

夏科氏脊柱关节病(CSA)在脊髓损伤患者中的发病率很可能正在上升。我们想强调这种疾病的初始症状、特定风险因素及围手术期并发症。德国BG创伤中心米尔瑙脊髓损伤专科医院的一项单中心回顾性病例系列研究,突出了夏科氏脊柱病治疗过程中的潜在障碍。我们描述了4例发生夏科氏脊柱关节病的截瘫女性患者(平均年龄:50.75岁;范围:42 - 67岁)。事故发生时的平均年龄为21.5岁(3 - 35岁),从事故发生到CSA发病并最终确诊的平均时间间隔为29.5年(17 - 39年),平均随访期为39.5个月(6 - 73个月)。文中提供了患者病史、初始症状、风险因素以及治疗和术后并发症情况。夏科氏脊柱病是脊髓损伤的一个重要潜在后遗症,可导致受影响个体出现严重残疾和脊柱急症。需要更多研究为脊柱外科医生提供更好的建议。保守治疗是一种选择。单纯后路固定似乎并不足够。

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本文引用的文献

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Do all Charcot Spine require surgery?所有夏科氏脊柱病变都需要手术吗?
Orthop Traumatol Surg Res. 2014 Nov;100(7):779-84. doi: 10.1016/j.otsr.2014.05.021. Epub 2014 Sep 23.
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8
Charcot spinal disease after spinal cord injury.脊髓损伤后夏科氏脊柱病
J Neurosurg Spine. 2008 Nov;9(5):419-26. doi: 10.3171/SPI.2008.9.11.419.
9
Surgical treatment of Charcot spine.夏科氏脊柱病的外科治疗
J Spinal Disord Tech. 2007 Feb;20(1):85-8. doi: 10.1097/01.bsd.0000211245.29458.03.
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Charcot's disease of the spine: diagnosis and treatment.脊柱夏科氏病:诊断与治疗
Spine (Phila Pa 1976). 2005 Jun 1;30(11):E315-22. doi: 10.1097/01.brs.0000164283.01454.9f.

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