Mitsui T, Kitta T, Moriya K, Takeda M, Shinohara N
Department of Urology, University of Yamanashi Graduate School of Medical Sciences, Chuo, Japan; Department of Urology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Department of Urology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Spinal Cord Ser Cases. 2015 Oct 8;1:15023. doi: 10.1038/scsandc.2015.23. eCollection 2015.
Long-term urodynamic and urological outcomes were evaluated in pediatric patients following traumatic spinal cord injury (SCI). The medical charts of three pediatric patients following traumatic SCI were retrospectively reviewed. The level of the injury was cervical in two patients and thoracic in one. Two patients, whose initial urodynamics demonstrated voluntary or reflex detrusor contraction with synergic sphincter relaxation, managed to void; however, urinary management was switched in one of these patients from voiding to clean intermittent catheterization (CIC) with anti-cholinergic agents because of a treatment for urinary incontinence. There were also no episodes of hydronephrosis, vesicoureteral reflux (VUR) or renal dysfunction in these two patients. Although one patient with hyperreflexic bladder was initially managed with CIC and anti-cholinergic agents, detrusor myectomy was ultimately performed because of severe VUR associated with the progressive worsening of lower urinary tract (LUT) function. Careful follow-ups including urodynamics are mandatory for children with progressively deteriorated LUT function or problematic urinary incontinence.
对创伤性脊髓损伤(SCI)后的儿科患者进行了长期尿动力学和泌尿系统转归评估。回顾性分析了3例创伤性SCI儿科患者的病历。2例患者损伤平面为颈椎,1例为胸椎。2例患者最初的尿动力学显示逼尿肌有自主或反射性收缩,伴协同性括约肌松弛,能够自行排尿;然而,其中1例患者因治疗尿失禁,将排尿方式改为使用抗胆碱能药物的清洁间歇性导尿(CIC)。这2例患者也未发生肾盂积水、膀胱输尿管反流(VUR)或肾功能障碍。尽管1例膀胱反射亢进患者最初采用CIC和抗胆碱能药物治疗,但由于严重VUR伴下尿路(LUT)功能逐渐恶化,最终进行了逼尿肌切除术。对于LUT功能逐渐恶化或存在问题性尿失禁的儿童,必须进行包括尿动力学检查在内的仔细随访。