Mahdavifar Neda, Ghoncheh Mahshid, Mohammadian-Hafshejani Abdollah, Khosravi Bahman, Salehiniya Hamid
Health Promotion Research Center, Department of Epidemiology and Biostatistics, School of Public Health, Zahedan University of Medical Sciences, Zahedan, Iran.
Department of Epidemiology and Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
Osong Public Health Res Perspect. 2016 Dec;7(6):360-372. doi: 10.1016/j.phrp.2016.11.002. Epub 2016 Nov 16.
One of the most common head and neck cancers is nasopharynx cancer. Knowledge about the incidence and mortality of this disease and its distribution in terms of geographical areas is necessary for further study and better planning. Therefore, this study was conducted with the aim of determining the incidence and mortality rates of nasopharynx cancer and its relationship with the Human Development Index (HDI) in Asia in 2012.
The aim of this ecologic study was to assess the correlation between age-specific incidence rate (ASIR) and age-specific mortality rate (ASMR) with HDI and its components, which include the following: life expectancy at birth, mean years of schooling, and gross national income per capita. Data about SIR and SMR for every Asian country for 2012 were obtained from the global cancer project. We used the correlation bivariate method for the assessment. Statistical significance was assumed if < 0.05. All reported values are two-sided. Statistical analyses were performed using SPSS (Version 15.0, SPSS Inc.).
A total of 68,272 cases (males, 71.02%; females, 28.97%; sex ratio, 2.45) and 40,530 mortalities (males, 71.63%; females, 28.36%; sex ratio, 2.52) were recorded in Asian countries in 2012. The five countries with the highest ASIR of nasopharynx cancer were Malaysia, Singapore, Indonesia, Vietnam, and Brunei, and the five countries with the highest ASMR were Indonesia, Vietnam, Singapore, Malaysia, and Brunei. The correlation between HDI and ASIR was 0.097 ( = 0.520) [0.105 in men ( = 0.488) and 0.119 in women ( = 0.901)]. The correlation between HDI and ASMR was -0.102 ( = 0.502) [-0.072 in men ( = 0.633) and -0.224 in women ( = 0.134)].
Nasopharynx cancer is native to Southeast Asia. The highest incidence and mortality rates are found in Malaysia, Singapore, Indonesia, Vietnam, and Brunei. No significant relation was found between the standardized incidence and mortality rates of nasopharynx cancer and the HDI components. Further studies are recommended in Southeast Asian countries in order to find the etiology of cancer, as well as its diagnosis and treatment.
鼻咽癌是最常见的头颈癌之一。了解该疾病的发病率、死亡率及其在地理区域上的分布情况，对于进一步研究和更好地规划至关重要。因此，本研究旨在确定2012年亚洲鼻咽癌的发病率和死亡率及其与人类发展指数（HDI）的关系。
本生态学研究旨在评估特定年龄发病率（ASIR）和特定年龄死亡率（ASMR）与HDI及其组成部分之间的相关性，HDI的组成部分包括：出生时预期寿命、平均受教育年限和人均国民总收入。2012年每个亚洲国家的SIR和SMR数据来自全球癌症项目。我们使用双变量相关方法进行评估。若P<0.05，则认为具有统计学意义。所有报告的P值均为双侧。使用SPSS（版本15.0，SPSS公司）进行统计分析。
2012年亚洲国家共记录了68272例病例（男性占71.02%；女性占28.97%；性别比为2.45）和40530例死亡（男性占71.63%；女性占28.36%；性别比为2.52）。鼻咽癌ASIR最高的五个国家是马来西亚、新加坡、印度尼西亚、越南和文莱，ASMR最高的五个国家是印度尼西亚、越南、新加坡、马来西亚和文莱。HDI与ASIR之间的相关性为0.097（P=0.520）[男性为0.105（P=0.488），女性为0.119（P=0.901）]。HDI与ASMR之间的相关性为-0.102（P=0.502）[男性为-0.072（P=0.633），女性为-0.224（P=0.134）]。
鼻咽癌原产于东南亚。马来西亚、新加坡、印度尼西亚、越南和文莱的发病率和死亡率最高。未发现鼻咽癌标准化发病率和死亡率与HDI组成部分之间存在显著关系。建议在东南亚国家开展进一步研究，以寻找癌症的病因及其诊断和治疗方法。
