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皮肤淋巴细胞瘤:颌面外科医生的诊断难题。

Lymphocytoma cutis: diagnostic enigma for the maxillofacial surgeon.

作者信息

Kale Tejraj P, Singh Arjun Gurmeet, Shah Pushpak

机构信息

Department of Oral and Maxillofacial Surgery, KLE Viswanath Katti Institute of Dental Sciences, KLE University, Belagavi, India.

Department of Oral Pathology and Microbiology, KLE Viswanath Katti Institute of Dental Sciences, KLE University, Belagavi, India.

出版信息

J Korean Assoc Oral Maxillofac Surg. 2016 Dec;42(6):379-382. doi: 10.5125/jkaoms.2016.42.6.379. Epub 2016 Dec 27.

Abstract

Cutaneous lymphoid hyperplasia (CLH) is a cutaneous pseudolymphoma with a worldwide distribution, equally affecting all races and ethnic groups. Due to its vast array of characteristics, it is most often missed in the differential diagnosis of firm to soft lumps on the head and neck. A systematic approach to the workup and diagnosis along with treatment of such lesions is discussed in this article. A 20-year-old Asian Indian female presented to our Oral and Maxillofacial unit with a lump on the left side of her forehead for 1 month. Local examination revealed a 2.5×3.0 cm, well circumscribed swelling over the left para median region that was firm to doughy and non-tender. There was no other significant finding on general examination. Excisional biopsy of the lesion was performed, followed by histopathologic processing. The general etiology, pathogenesis, clinical presentation, differential diagnosis, clinical course, prognosis, treatment, and prevention have been discussed in line with the recent modalities of diagnosis and treatment of CLH. Due to the overlapping clinical and histological characteristics of CLH with many other lesions, it is important to consider this lesion in the differential diagnosis of cutaneous lesions.

摘要

皮肤淋巴细胞增生症(CLH)是一种皮肤假性淋巴瘤,在全球范围内均有分布,对所有种族和民族的影响相同。由于其具有众多特征,在头颈部质地硬至软的肿块鉴别诊断中常被漏诊。本文讨论了对此类病变进行检查、诊断及治疗的系统方法。一名20岁的亚洲印度女性因前额左侧出现肿块1个月前来我们的口腔颌面科就诊。局部检查发现左旁正中区域有一个2.5×3.0厘米、边界清晰的肿胀,质地硬至柔韧,无压痛。全身检查未发现其他明显异常。对病变进行了切除活检,随后进行了组织病理学处理。本文根据CLH诊断和治疗的最新模式,对其一般病因、发病机制、临床表现、鉴别诊断、临床病程、预后、治疗及预防进行了讨论。由于CLH与许多其他病变在临床和组织学特征上存在重叠,因此在皮肤病变的鉴别诊断中考虑该病变很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38b1/5206245/17dd94a186b4/jkaoms-42-379-g001.jpg

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