Mahmood Farhan, Teo Iris Yh, Kirchhof Mark G
Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, ON, Canada.
SAGE Open Med Case Rep. 2021 Jun 14;9:2050313X211025104. doi: 10.1177/2050313X211025104. eCollection 2021.
Lymphocytoma cutis reflects an exaggerated local immunologic reaction to a stimulus presenting on the head, neck, or upper extremities as a firm 1-3 cm erythematous and/or violaceous plaque or nodule. However, lymphocytoma cutis may be difficult to treat due to the variety of causative agents and the lack of reported successful treatments and outcomes. Here, we present a case of 68-year-old female with recalcitrant lymphocytoma cutis resistant to other first-line therapies including tacrolimus ointment and steroids. The red plaque on the patient's left cheek was eventually treated with mycophenolate mofetil. Mycophenolate mofetil was an accessible and effective therapeutic option to treat lymphocytoma cutis with minimal side effects.
皮肤淋巴细胞瘤反映了机体对头部、颈部或上肢出现的刺激物产生的过度局部免疫反应，表现为坚实的1 - 3厘米红斑和/或紫红斑块或结节。然而，由于致病因素的多样性以及缺乏已报道的成功治疗方法和结果，皮肤淋巴细胞瘤可能难以治疗。在此，我们报告一例68岁女性，患有顽固性皮肤淋巴细胞瘤，对包括他克莫司软膏和类固醇在内的其他一线治疗均耐药。患者左脸颊上的红色斑块最终用霉酚酸酯进行了治疗。霉酚酸酯是一种可及且有效的治疗皮肤淋巴细胞瘤的选择，副作用极小。
