Zhaohua Yin, Wei Feng, Fei Xu, Jiqiang Zhang, Junzhe Du, Yangwu Song
Department of Cardiac Surgery, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Heart Surg Forum. 2016 Dec 6;19(6):E272-E275. doi: 10.1532/hsf.1630.
To evaluate the effects of combined coronary artery bypass grafting (CABG), surgical left ventricular restoration (LVR), and mitral valve repair (MVP) in treating ischemic heart disease combined with mitral regurgitation; and to evaluate the different strategies of LVR and MVP.
From January 2001 to December 2015, 61 consecutive patients with left ventricular aneurysm and ischemic mitral regurgitation underwent concomitant CABG, LVR and MVP. We evaluated the clinical and echocardiographic outcomes of the patients. The mean follow-up was 5.8 ± 3.3 years.
The operative mortality was 4.9%. One-, five-, and ten-year survival rates were 95.1%, 86.9%, and 80.3%, respectively. Mitral regurgitation, left ventricular ejection fraction (LVEF), and left ventricular end diastolic diameter (LVEDD) improved significantly after surgery (P < .001). During follow-up, 3 patients (5.2%) had moderate mitral regurgitation and 1 patient (1.9%) had severe mitral regurgitation. The clinical outcomes were not influenced by the LVR technique and MVP approach.
Combined CABG, LVR, and MVP was effective for ischemic left ventricular aneurysm with mitral regurgitation. The procedure was associated with acceptable operative risk and clinical outcomes.
评估冠状动脉旁路移植术(CABG)、外科左心室修复术(LVR)和二尖瓣修复术(MVP)联合治疗缺血性心脏病合并二尖瓣反流的效果;并评估LVR和MVP的不同策略。
2001年1月至2015年12月,61例连续性左心室室壁瘤合并缺血性二尖瓣反流患者接受了同期CABG、LVR和MVP治疗。我们评估了患者的临床和超声心动图结果。平均随访时间为5.8±3.3年。
手术死亡率为4.9%。1年、5年和10年生存率分别为95.1%、86.9%和80.3%。术后二尖瓣反流、左心室射血分数(LVEF)和左心室舒张末期内径(LVEDD)均显著改善(P<.001)。随访期间,3例患者(5.2%)出现中度二尖瓣反流,1例患者(1.9%)出现重度二尖瓣反流。临床结果不受LVR技术和MVP方法的影响。
CABG、LVR和MVP联合应用对缺血性左心室室壁瘤合并二尖瓣反流有效。该手术具有可接受的手术风险和临床结果。