Melville Laboratory for Polymer Synthesis, Department of Chemistry, University of Cambridge , Lensfield Road, Cambridge, CB2 1EW, United Kingdom.
Department of Chemistry, Tsinghua University , Beijing 100084, China.
Langmuir. 2017 Feb 14;33(6):1343-1350. doi: 10.1021/acs.langmuir.6b03457. Epub 2017 Feb 3.
Cucurbit[8]uril (CB[8]) heteroternary complexes display certain characteristics making them well-suited for molecular level adhesives. In particular, careful choice of host-guest binding pairs enables specific, fully reversible adhesion. Understanding the effect of the environment is also critical when developing new molecular level adhesives. Here we explore the binding forces involved in the methyl viologen·CB[8]·naphthol heteroternary complex using single-molecule force spectroscopy (SMFS) under a variety of conditions. From SMFS, the interaction of a single ternary complex was found to be in the region of 140 pN. Additionally, a number of surface interactions could be readily differentiated using the SMFS technique allowing for a deeper understanding of the dynamic heteroternary CB[8] system on the single-molecule scale.
葫芦脲（CB[8]）杂合三元配合物具有某些特性，使其非常适合作为分子级别的黏合剂。特别是，通过仔细选择主客体结合对，可以实现特定的、完全可逆的黏附。在开发新型分子级别的黏合剂时，了解环境的影响也至关重要。在这里，我们使用各种条件下的单分子力谱（SMFS）技术研究了甲基紫精·CB[8]·萘酚杂合三元配合物中涉及的结合力。通过 SMFS，发现单个三元配合物的相互作用在 140pN 左右。此外，还可以使用 SMFS 技术轻松区分许多表面相互作用，从而更深入地了解单分子水平上动态杂合 CB[8]系统。
