Zhang Suojun, Wang Sheng, Wan Xueyan, Liu Shengwen, Shu Kai, Lei Ting
a Department of Neurosurgery , Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , PR China.
Brain Inj. 2017;31(2):215-220. doi: 10.1080/02699052.2016.1227088. Epub 2017 Jan 5.
Patients with traumatic epidural haematoma, undergoing the prompt and correct treatment, usually have favourable outcomes. However, secondary cerebral infarction may be life-threatening condition, as it is difficult to be identified before neurological impairment occurs.
To evaluate the clinical data of patients with traumatic EDH and assess potential risk factors for post-operative cerebral infarction.
The clinical data of patients with traumatic EDH were collected and analysed retrospectively.
The univariate analysis revealed 10 potential risk factors (the haematoma location, volume, the largest thickness and mid-line shift, basal cisterns compression, traumatic subarachnoid haemorrhage, pupil dilatation, pre-operative Glasgow Coma Scale score, ∆GCS and intraoperative brain pressure) for cerebral infarction with statistically significant difference. Of these factors, haematoma volume and basal cistern compression turned out to be the most significant risk factors through final multivariate logistic regression analysis.
The findings of this study can provide predictive factors for development of cerebral infarction and information for clinical decision-making and future studies.
外伤性硬膜外血肿患者若接受及时、正确的治疗,通常预后良好。然而,继发性脑梗死可能是危及生命的情况,因为在神经功能缺损出现之前很难识别。
评估外伤性硬膜外血肿患者的临床资料,并评估术后脑梗死的潜在危险因素。
回顾性收集并分析外伤性硬膜外血肿患者的临床资料。
单因素分析显示10个脑梗死潜在危险因素(血肿位置、体积、最大厚度和中线移位、基底池受压、外伤性蛛网膜下腔出血、瞳孔散大、术前格拉斯哥昏迷量表评分、格拉斯哥昏迷量表评分变化及术中脑压)有统计学显著差异。在这些因素中,通过最终多因素逻辑回归分析,血肿体积和基底池受压是最显著的危险因素。
本研究结果可为脑梗死的发生提供预测因素,并为临床决策和未来研究提供信息。