a Department of Genetics and Molecular Medicine , Vasavi Medical and Research Center , Hyderabad , India.
b Department of Clinical Pharmacology , Apollo Hospital, Jubilee Hills , Hyderabad , India.
Clin Exp Hypertens. 2017;39(1):1-7. doi: 10.1080/10641963.2016.1210627. Epub 2017 Jan 5.
Several association studies have been carried out to elucidate the role of genetic variants in cardiovascular diseases (CVDs), while studies on the epigenome regulating gene expression changes are helping to understand the development of disease and factors promoting such changes. This review summarizes the different epigenetic aspects involved in cardiac development and disease along with current therapeutic interventions.
已经进行了几项关联研究，以阐明遗传变异在心血管疾病（CVDs）中的作用，而关于调节基因表达变化的表观基因组学的研究有助于了解疾病的发展和促进这些变化的因素。本综述总结了心脏发育和疾病中涉及的不同表观遗传方面以及当前的治疗干预措施。
